Practical tantalum coating of microspheres for experimental visualization under fluoroscopy and CT

Masahiro Horikawa, Masaki Ishikawa, Barry Uchida, John Kaufman, Khashayar Farsad

Research output: Contribution to journalArticle


The present report describes a simple technique for tantalum coating of microspheres for visualization by fluoroscopy and computed tomography (CT). Spherical microspheres were soaked with Ta powder under different conditions and microscopically evaluated for Ta-coating quality by assessing bound and unbound Ta. For 100-300-μm Embosphere particles, soaking with 0.05 mL Ta powder for 30 minutes and centrifugation at 500 rpm produced optimal coating. Optimized microspheres were injected in swine renal arteries and assessed by fluoroscopy and micro-CT for the opacification of segmental, arcuate, and interlobular arteries. This practical method can be used for experimental studies with commonly available microspheres.

Original languageEnglish (US)
Pages (from-to)127-132
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Issue number1
Publication statusPublished - Jan 1 2016


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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