Practical tantalum coating of microspheres for experimental visualization under fluoroscopy and CT

Masahiro Horikawa; Masaki Ishikawa; Barry Uchida; John Kaufman; Khashayar Farsad

doi:10.1016/j.jvir.2015.07.028

Practical tantalum coating of microspheres for experimental visualization under fluoroscopy and CT

Masahiro Horikawa, Masaki Ishikawa, Barry Uchida, John Kaufman, Khashayar Farsad

Dotter Interventional Institute

Research output: Contribution to journal › Article › peer-review

Abstract

The present report describes a simple technique for tantalum coating of microspheres for visualization by fluoroscopy and computed tomography (CT). Spherical microspheres were soaked with Ta powder under different conditions and microscopically evaluated for Ta-coating quality by assessing bound and unbound Ta. For 100-300-μm Embosphere particles, soaking with 0.05 mL Ta powder for 30 minutes and centrifugation at 500 rpm produced optimal coating. Optimized microspheres were injected in swine renal arteries and assessed by fluoroscopy and micro-CT for the opacification of segmental, arcuate, and interlobular arteries. This practical method can be used for experimental studies with commonly available microspheres.

Original language	English (US)
Pages (from-to)	127-132
Number of pages	6
Journal	Journal of Vascular and Interventional Radiology
Volume	27
Issue number	1
DOIs	https://doi.org/10.1016/j.jvir.2015.07.028
State	Published - Jan 1 2016

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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abstract = "The present report describes a simple technique for tantalum coating of microspheres for visualization by fluoroscopy and computed tomography (CT). Spherical microspheres were soaked with Ta powder under different conditions and microscopically evaluated for Ta-coating quality by assessing bound and unbound Ta. For 100-300-μm Embosphere particles, soaking with 0.05 mL Ta powder for 30 minutes and centrifugation at 500 rpm produced optimal coating. Optimized microspheres were injected in swine renal arteries and assessed by fluoroscopy and micro-CT for the opacification of segmental, arcuate, and interlobular arteries. This practical method can be used for experimental studies with commonly available microspheres.",

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