Abstract
We describe our experience using the posaconazole 400-mg delayed-release tablet formulation once daily in 20 patients with hematologic malignancy or hematopoietic stem cell transplant who were unable to attain prespecified target minimum serum (trough) concentrations for treatment or prophylaxis of invasive fungal infection. The higher dose allowed the majority of patients to achieve prespecified target trough concentrations without incurring additional toxicities.
Original language | English (US) |
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Pages (from-to) | 6945-6947 |
Number of pages | 3 |
Journal | Antimicrobial agents and chemotherapy |
Volume | 60 |
Issue number | 11 |
DOIs | |
State | Published - Nov 1 2016 |
ASJC Scopus subject areas
- Pharmacology
- Pharmacology (medical)
- Infectious Diseases