Polyurethane-coated Dacron-covered stentgrafts for tips: Results in swine

Robert Bloch, Dusan Pavcnik, Barry T. Uchida, Antonin Krajina, Toshio Kamino, Hans Timmermans, Marc Loriaux, Peter Hulek

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Purpose: To evaluate shunt patency after placing a new polyurethane- coated Dacron-covered spiral Z stent-graft to create a transjugular intrahepatic portosystemic shunt (TIPS). Methods: TIPS stent-grafts were placed in six young swine, using polyurethane-coated, Dacron-covered spiral Z stent-grafts. Animals were followed weekly by transhepatic portal venography until shunt occlusion or up to 6 weeks, then were sacrificed for gross and histologic evaluation. Results: Five of six TIPS stent-grafts were found to be occluded by 3 weeks and none were patent at 6 weeks. Histologic evaluation demonstrated a marked foreign body reaction with superimposed thrombosis occluding the graft lumen. Conclusion: Polyurethane-coated Dacron-covered stentgrafts do not improve TIPS patency.

Original languageEnglish (US)
Pages (from-to)497-500
Number of pages4
JournalCardiovascular and interventional radiology
Volume21
Issue number6
DOIs
StatePublished - Nov 1 1998

Keywords

  • Dacron spiral Z stent-graft
  • Transjugular intrahepatic portosystemic shunt (TIPS) Dacron-covered stentgrafts

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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