Polyurethane-coated Dacron-covered stentgrafts for tips: Results in swine

Robert Bloch; Dusan Pavcnik; Barry T. Uchida; Antonin Krajina; Toshio Kamino; Hans Timmermans; Marc Loriaux; Peter Hulek

doi:10.1007/s002709900310

Polyurethane-coated Dacron-covered stentgrafts for tips: Results in swine

Robert Bloch, Dusan Pavcnik, Barry T. Uchida, Antonin Krajina, Toshio Kamino, Hans Timmermans, Marc Loriaux, Peter Hulek

Pathology

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Purpose: To evaluate shunt patency after placing a new polyurethane- coated Dacron-covered spiral Z stent-graft to create a transjugular intrahepatic portosystemic shunt (TIPS). Methods: TIPS stent-grafts were placed in six young swine, using polyurethane-coated, Dacron-covered spiral Z stent-grafts. Animals were followed weekly by transhepatic portal venography until shunt occlusion or up to 6 weeks, then were sacrificed for gross and histologic evaluation. Results: Five of six TIPS stent-grafts were found to be occluded by 3 weeks and none were patent at 6 weeks. Histologic evaluation demonstrated a marked foreign body reaction with superimposed thrombosis occluding the graft lumen. Conclusion: Polyurethane-coated Dacron-covered stentgrafts do not improve TIPS patency.

Original language	English (US)
Pages (from-to)	497-500
Number of pages	4
Journal	Cardiovascular and interventional radiology
Volume	21
Issue number	6
DOIs	https://doi.org/10.1007/s002709900310
State	Published - Nov 1998

Keywords

Dacron spiral Z stent-graft
Transjugular intrahepatic portosystemic shunt (TIPS) Dacron-covered stentgrafts

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1007/s002709900310

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@article{c8eee5bc9a9a41c19f819b7c8b93346d,

title = "Polyurethane-coated Dacron-covered stentgrafts for tips: Results in swine",

abstract = "Purpose: To evaluate shunt patency after placing a new polyurethane- coated Dacron-covered spiral Z stent-graft to create a transjugular intrahepatic portosystemic shunt (TIPS). Methods: TIPS stent-grafts were placed in six young swine, using polyurethane-coated, Dacron-covered spiral Z stent-grafts. Animals were followed weekly by transhepatic portal venography until shunt occlusion or up to 6 weeks, then were sacrificed for gross and histologic evaluation. Results: Five of six TIPS stent-grafts were found to be occluded by 3 weeks and none were patent at 6 weeks. Histologic evaluation demonstrated a marked foreign body reaction with superimposed thrombosis occluding the graft lumen. Conclusion: Polyurethane-coated Dacron-covered stentgrafts do not improve TIPS patency.",

keywords = "Dacron spiral Z stent-graft, Transjugular intrahepatic portosystemic shunt (TIPS) Dacron-covered stentgrafts",

author = "Robert Bloch and Dusan Pavcnik and Uchida, {Barry T.} and Antonin Krajina and Toshio Kamino and Hans Timmermans and Marc Loriaux and Peter Hulek",

year = "1998",

month = nov,

doi = "10.1007/s002709900310",

language = "English (US)",

volume = "21",

pages = "497--500",

journal = "Cardiovascular and interventional radiology",

issn = "0174-1551",

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TY - JOUR

T1 - Polyurethane-coated Dacron-covered stentgrafts for tips

T2 - Results in swine

AU - Bloch, Robert

AU - Pavcnik, Dusan

AU - Uchida, Barry T.

AU - Krajina, Antonin

AU - Kamino, Toshio

AU - Timmermans, Hans

AU - Loriaux, Marc

AU - Hulek, Peter

PY - 1998/11

Y1 - 1998/11

N2 - Purpose: To evaluate shunt patency after placing a new polyurethane- coated Dacron-covered spiral Z stent-graft to create a transjugular intrahepatic portosystemic shunt (TIPS). Methods: TIPS stent-grafts were placed in six young swine, using polyurethane-coated, Dacron-covered spiral Z stent-grafts. Animals were followed weekly by transhepatic portal venography until shunt occlusion or up to 6 weeks, then were sacrificed for gross and histologic evaluation. Results: Five of six TIPS stent-grafts were found to be occluded by 3 weeks and none were patent at 6 weeks. Histologic evaluation demonstrated a marked foreign body reaction with superimposed thrombosis occluding the graft lumen. Conclusion: Polyurethane-coated Dacron-covered stentgrafts do not improve TIPS patency.

AB - Purpose: To evaluate shunt patency after placing a new polyurethane- coated Dacron-covered spiral Z stent-graft to create a transjugular intrahepatic portosystemic shunt (TIPS). Methods: TIPS stent-grafts were placed in six young swine, using polyurethane-coated, Dacron-covered spiral Z stent-grafts. Animals were followed weekly by transhepatic portal venography until shunt occlusion or up to 6 weeks, then were sacrificed for gross and histologic evaluation. Results: Five of six TIPS stent-grafts were found to be occluded by 3 weeks and none were patent at 6 weeks. Histologic evaluation demonstrated a marked foreign body reaction with superimposed thrombosis occluding the graft lumen. Conclusion: Polyurethane-coated Dacron-covered stentgrafts do not improve TIPS patency.

KW - Dacron spiral Z stent-graft

KW - Transjugular intrahepatic portosystemic shunt (TIPS) Dacron-covered stentgrafts

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DO - 10.1007/s002709900310

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SN - 0174-1551

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SP - 497

EP - 500

JO - Cardiovascular and interventional radiology

JF - Cardiovascular and interventional radiology

IS - 6

ER -

Polyurethane-coated Dacron-covered stentgrafts for tips: Results in swine

Abstract

Keywords

ASJC Scopus subject areas

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