Polysomnographic respiratory abnormalities in asymptomatic individuals

Milena K. Pavlova, Jeanne F. Duffy, Steven Shea

Research output: Contribution to journalArticle

71 Scopus citations


Study objectives: Polysomnographic respiratory abnormalities have been extensively studied in the general population, but studies have not targeted completely healthy individuals. We aimed to (1) define the frequency of respiratory disturbances (RDI: events per hour of sleep) during sleep in healthy individuals using current techniques and criteria and (2) determine how these abnormalities change with age and sex. Design and Setting: Cross-sectional analyses of RDI in healthy volunteers. Participants: One hundred sixty-three individuals (106 men) were screened for chronic medical illness, as confirmed by extensive questionnaires, physical examination, electrocardiography, and laboratory analysis. Obese subjects (body mass index > 30 kg/m2) and subjects taking medications were excluded. Interventions, Measurements and Results: Subjects underwent full polysomnography using current standard recording and scoring techniques. There was a remarkable increase in RDI with age, particularly over 50 years. Ninety-five percent of currently healthy subjects under 50 years of age had an RDI

Original languageEnglish (US)
Pages (from-to)241-248
Number of pages8
Issue number2
Publication statusPublished - 2008
Externally publishedYes



  • Aging
  • Healthy
  • Normal
  • Sleep apnea
  • Sleep-disordered breathing

ASJC Scopus subject areas

  • Physiology

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