Platypnea-Orthodeoxia Syndrome: A Case of Chronic Paroxysmal Hypoxemia

C. Craig Rudy, Cody Ballard, Craig Broberg, Alan Hunter

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 75-year-old man with chronic (30-year) unexplained paroxysmal hypoxemia presented with postural hypoxemia and desaturation consistent with a clinical manifestation of platypnea-orthodeoxia syndrome. His history included a lack of significant past pulmonary disease, yet with intermittent need for oxygen supplementation. On admission he was found to have an interatrial shunt through a patent foramen ovale. Device closure by percutaneous catheterization led to sustained resolution of symptoms. Platypnea-orthodeoxia syndrome is a rare but important consideration in the differential diagnosis of hypoxemia, as it represents a potentially curable cause of hypoxemia, with missed diagnosis leading to possible patient morbidity if untreated. Even more importantly, an astute and careful history and physical examination are integral to the diagnosis of this rare but likely under-recognized syndrome.

Original languageEnglish (US)
Pages (from-to)1-4
Number of pages4
JournalJournal of General Internal Medicine
DOIs
StateAccepted/In press - Oct 26 2016

Fingerprint

History
Patent Foramen Ovale
Lung Diseases
Physical Examination
Differential Diagnosis
Oxygen
Morbidity
Hypoxia
Vascular Closure Devices

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Platypnea-Orthodeoxia Syndrome : A Case of Chronic Paroxysmal Hypoxemia. / Rudy, C. Craig; Ballard, Cody; Broberg, Craig; Hunter, Alan.

In: Journal of General Internal Medicine, 26.10.2016, p. 1-4.

Research output: Contribution to journalArticle

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