Abstract
Plasma concentrations of dehydroepiandrosterone, 17-hydroxypregnenolone, Δ5- androstenediol, 17-hydroxyprogesterone, progesterone, cortisol and 21-deoxycortisol were measured in 8 patients with the 21-hydroxylase deficiency type of congenital adrenal hyperplasia. In contrast to 17-hydroxyprogesterone, which was elevated as much as 100-fold, the Δ5-steroids were elevated only about 2-fold when compared to normal adult values. Plasma progesterone in 3 salt-losing siblings was about 5 times that of the nonsalt-losing subjects. Plasma 21-deoxycortisol averaged about 25 ng/ml, compared to an average of 0.3 ng/ml in normal subjects.
Original language | English (US) |
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Pages (from-to) | 627-630 |
Number of pages | 4 |
Journal | Journal of Clinical Endocrinology and Metabolism |
Volume | 39 |
Issue number | 4 |
DOIs | |
State | Published - Oct 1974 |
Externally published | Yes |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Biochemistry
- Endocrinology
- Clinical Biochemistry
- Biochemistry, medical