Plague meningitis - a retrospective analysis of cases reported in the United States, 1970-1979

Thomas Becker, J. D. Poland, T. J. Quan, M. E. White, J. M. Mann, A. M. Barnes

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Meningitis caused by Yersinia pestis developed in 6 (6%) of a total of 105 patients with plague reported to the Centers for Disease Control from 1970 to 1979. Five of the six cases occurred in childeren aged 10 to 15 years. All six patients received antibiotic therapy before meningitis developed, which appeared between the 9th and 14th days after the onset of acute illness in five of the six patients. There were no neurologic sequelae. The antigenic and biochemical profiles of the Y pestis strains isolated from cerebrospinal fluid in the meningitis cases did not differ from those of the Y pestis strains obtained from blood and bubo aspirates in the other 99 patients, and neither did in vitro studies suggest antibiotic resistance. While plague meningitis is an uncommon complication of acute plague infection, physicians in the western United States should be aware that it may develop as much as 14 days after antibiotic therapy for the acute plague infection has been initiated.

Original languageEnglish (US)
Pages (from-to)554-557
Number of pages4
JournalWestern Journal of Medicine
Volume147
Issue number5
StatePublished - 1987
Externally publishedYes

Fingerprint

Plague
Meningitis
Anti-Bacterial Agents
Yersinia pestis
Centers for Disease Control and Prevention (U.S.)
Microbial Drug Resistance
Infection
Nervous System
Cerebrospinal Fluid
Physicians
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Becker, T., Poland, J. D., Quan, T. J., White, M. E., Mann, J. M., & Barnes, A. M. (1987). Plague meningitis - a retrospective analysis of cases reported in the United States, 1970-1979. Western Journal of Medicine, 147(5), 554-557.

Plague meningitis - a retrospective analysis of cases reported in the United States, 1970-1979. / Becker, Thomas; Poland, J. D.; Quan, T. J.; White, M. E.; Mann, J. M.; Barnes, A. M.

In: Western Journal of Medicine, Vol. 147, No. 5, 1987, p. 554-557.

Research output: Contribution to journalArticle

Becker, T, Poland, JD, Quan, TJ, White, ME, Mann, JM & Barnes, AM 1987, 'Plague meningitis - a retrospective analysis of cases reported in the United States, 1970-1979', Western Journal of Medicine, vol. 147, no. 5, pp. 554-557.
Becker, Thomas ; Poland, J. D. ; Quan, T. J. ; White, M. E. ; Mann, J. M. ; Barnes, A. M. / Plague meningitis - a retrospective analysis of cases reported in the United States, 1970-1979. In: Western Journal of Medicine. 1987 ; Vol. 147, No. 5. pp. 554-557.
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