Physiopathology of the cochlear microcirculation

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Normal blood supply to the cochlea is critically important for establishing the endocochlear potential and sustaining production of endolymph. Abnormal cochlear microcirculation has long been considered an etiologic factor in noise-induced hearing loss, age-related hearing loss (presbycusis), sudden hearing loss or vestibular function, and Meniere's disease. Knowledge of the mechanisms underlying the pathophysiology of cochlear microcirculation is of fundamental clinical importance. A better understanding of cochlear blood flow (CoBF) will enable more effective management of hearing disorders resulting from aberrant blood flow. This review focuses on recent discoveries and findings related to the physiopathology of the cochlear microvasculature.

Original languageEnglish (US)
Pages (from-to)10-24
Number of pages15
JournalHearing Research
Volume282
Issue number1-2
DOIs
StatePublished - Dec 2011

Fingerprint

Cochlea
Microcirculation
Vestibular Diseases
Presbycusis
Endolymph
Hearing Disorders
Noise-Induced Hearing Loss
Sudden Hearing Loss
Meniere Disease
Microvessels
Hearing Loss

ASJC Scopus subject areas

  • Sensory Systems

Cite this

Physiopathology of the cochlear microcirculation. / Shi, Xiao.

In: Hearing Research, Vol. 282, No. 1-2, 12.2011, p. 10-24.

Research output: Contribution to journalArticle

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