Physical activity and the risk of breast cancer recurrence: A literature review

Paul D. Loprinzi, Bradley J. Cardinal, Kerri Winters-Stone, Ellen Smit, Charles L. Loprinzi

Research output: Contribution to journalReview articlepeer-review

58 Scopus citations

Abstract

Purpose/Objectives: To examine the association between physical activity and breast cancer mortality and recurrence, and to provide an overview of factors related to physical activity behavior in women with breast cancer. Data Sources: An extensive review of the epidemiologic literature on the effect of physical activity on breast cancer recurrence and mortality was conducted using PubMed up to December 2010, involving the following key words: physical activity, exercise, breast cancer, breast cancer recurrence, and breast cancer mortality. Data Synthesis: For breast cancer recurrence and breast cancer-related mortality, studies were included if physical activity served as the independent variable and a measure of association was reported. To examine determinants of physical activity, studies were included if a hypothesized factor served as the independent variable and a measure of association was reported. Conclusions: Of the six studies that examined the influence of physical activity on breast cancer mortality, four (67%) reported a protective effect (i.e., inverse association), two examined the influence of physical activity on breast cancer recurrence and reported a nonsignificant risk reduction. Few studies have examined factors that influence physical activity behavior in women with breast cancer, and findings suggest that psychosocial factors play an important role in influencing the activity patterns of breast cancer survivors. Future longitudinal studies are needed to confirm those findings. Implications for Nursing: To prevent breast cancer recurrence and breast cancer-related mortality, nurses should encourage breast cancer survivors to engage in regular exercise.

Original languageEnglish (US)
Pages (from-to)269-274
Number of pages6
JournalOncology nursing forum
Volume39
Issue number3
DOIs
StatePublished - May 2012

ASJC Scopus subject areas

  • Oncology(nursing)

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