Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation

Daniel J. McAuliffe, Steven L. Jacques, Amy S. Hayes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

A striking consequence of 248-nm excimer laser irradiation of skin is a stable vivid blue fluorescence easily visualized under UVA illumination. Its spectral properties (excitation maximum at approximately 335 nm; emission maximum at approximately 430 nm) are somewhat similar to those of the fluorescent pigments associated with aging of tissue and peroxidation of lipids, and the fluorescent pigments formed during exposure to high temperatures. This study explores the spectral properties, magnitude, dose response, and laser pulse intensity dependence of this phenomenon in both isolated stratum corneum and epidermal cell suspensions from human skin.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsSteven L. Jacques
PublisherPubl by Int Soc for Optical Engineering
Pages93-102
Number of pages10
ISBN (Print)0819402435
StatePublished - Dec 1 1990
Externally publishedYes
EventProceedings of Laser-Tissue Interaction - Los Angeles, CA, USA
Duration: Jan 15 1990Jan 17 1990

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1202
ISSN (Print)0277-786X

Other

OtherProceedings of Laser-Tissue Interaction
CityLos Angeles, CA, USA
Period1/15/901/17/90

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    McAuliffe, D. J., Jacques, S. L., & Hayes, A. S. (1990). Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation. In S. L. Jacques (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (pp. 93-102). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1202). Publ by Int Soc for Optical Engineering.