Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation

Daniel J. McAuliffe, Steven Jacques, Amy S. Hayes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

A striking consequence of 248-nm excimer laser irradiation of skin is a stable vivid blue fluorescence easily visualized under UVA illumination. Its spectral properties (excitation maximum at approximately 335 nm; emission maximum at approximately 430 nm) are somewhat similar to those of the fluorescent pigments associated with aging of tissue and peroxidation of lipids, and the fluorescent pigments formed during exposure to high temperatures. This study explores the spectral properties, magnitude, dose response, and laser pulse intensity dependence of this phenomenon in both isolated stratum corneum and epidermal cell suspensions from human skin.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsSteven L. Jacques
PublisherPubl by Int Soc for Optical Engineering
Pages93-102
Number of pages10
Volume1202
ISBN (Print)0819402435
StatePublished - 1990
Externally publishedYes
EventProceedings of Laser-Tissue Interaction - Los Angeles, CA, USA
Duration: Jan 15 1990Jan 17 1990

Other

OtherProceedings of Laser-Tissue Interaction
CityLos Angeles, CA, USA
Period1/15/901/17/90

Fingerprint

Excimer lasers
Laser beam effects
pigments
Pigments
excimer lasers
Skin
Tissue
irradiation
cornea
strata
Lipids
lipids
Laser pulses
Aging of materials
Lighting
Fluorescence
illumination
dosage
fluorescence
pulses

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

McAuliffe, D. J., Jacques, S., & Hayes, A. S. (1990). Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation. In S. L. Jacques (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 1202, pp. 93-102). Publ by Int Soc for Optical Engineering.

Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation. / McAuliffe, Daniel J.; Jacques, Steven; Hayes, Amy S.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Steven L. Jacques. Vol. 1202 Publ by Int Soc for Optical Engineering, 1990. p. 93-102.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

McAuliffe, DJ, Jacques, S & Hayes, AS 1990, Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation. in SL Jacques (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 1202, Publ by Int Soc for Optical Engineering, pp. 93-102, Proceedings of Laser-Tissue Interaction, Los Angeles, CA, USA, 1/15/90.
McAuliffe DJ, Jacques S, Hayes AS. Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation. In Jacques SL, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1202. Publ by Int Soc for Optical Engineering. 1990. p. 93-102
McAuliffe, Daniel J. ; Jacques, Steven ; Hayes, Amy S. / Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation. Proceedings of SPIE - The International Society for Optical Engineering. editor / Steven L. Jacques. Vol. 1202 Publ by Int Soc for Optical Engineering, 1990. pp. 93-102
@inproceedings{3dfa5319c8bf40f39cbd5841e8d7f9c9,
title = "Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation",
abstract = "A striking consequence of 248-nm excimer laser irradiation of skin is a stable vivid blue fluorescence easily visualized under UVA illumination. Its spectral properties (excitation maximum at approximately 335 nm; emission maximum at approximately 430 nm) are somewhat similar to those of the fluorescent pigments associated with aging of tissue and peroxidation of lipids, and the fluorescent pigments formed during exposure to high temperatures. This study explores the spectral properties, magnitude, dose response, and laser pulse intensity dependence of this phenomenon in both isolated stratum corneum and epidermal cell suspensions from human skin.",
author = "McAuliffe, {Daniel J.} and Steven Jacques and Hayes, {Amy S.}",
year = "1990",
language = "English (US)",
isbn = "0819402435",
volume = "1202",
pages = "93--102",
editor = "Jacques, {Steven L.}",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "Publ by Int Soc for Optical Engineering",

}

TY - GEN

T1 - Photochemical and thermal changes in tissue autofluorescence during excimer laser irradiation

AU - McAuliffe, Daniel J.

AU - Jacques, Steven

AU - Hayes, Amy S.

PY - 1990

Y1 - 1990

N2 - A striking consequence of 248-nm excimer laser irradiation of skin is a stable vivid blue fluorescence easily visualized under UVA illumination. Its spectral properties (excitation maximum at approximately 335 nm; emission maximum at approximately 430 nm) are somewhat similar to those of the fluorescent pigments associated with aging of tissue and peroxidation of lipids, and the fluorescent pigments formed during exposure to high temperatures. This study explores the spectral properties, magnitude, dose response, and laser pulse intensity dependence of this phenomenon in both isolated stratum corneum and epidermal cell suspensions from human skin.

AB - A striking consequence of 248-nm excimer laser irradiation of skin is a stable vivid blue fluorescence easily visualized under UVA illumination. Its spectral properties (excitation maximum at approximately 335 nm; emission maximum at approximately 430 nm) are somewhat similar to those of the fluorescent pigments associated with aging of tissue and peroxidation of lipids, and the fluorescent pigments formed during exposure to high temperatures. This study explores the spectral properties, magnitude, dose response, and laser pulse intensity dependence of this phenomenon in both isolated stratum corneum and epidermal cell suspensions from human skin.

UR - http://www.scopus.com/inward/record.url?scp=0025596784&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025596784&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:0025596784

SN - 0819402435

VL - 1202

SP - 93

EP - 102

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Jacques, Steven L.

PB - Publ by Int Soc for Optical Engineering

ER -