Photoacoustic imaging of buried objects using an all-optical detection scheme

Peter E. Andersen, Steen G. Hanson, Steven L. Jacques

Research output: Contribution to journalConference articlepeer-review

Abstract

Photoacoustic imaging may become an important imaging tool for several diagnostic procedures, e.g. as an alternative to mammography. Imaging of large objects, sub-mm to mm sized, buried deep in optically turbid tissue is feasible. Our investigation is primarily concentrated on characterizing a photoacoustic imaging system based on an all-optical detection scheme experimentally. The optical detection scheme is based on a novel dual-beam common path interferometer. The experimental investigation is carried out using a phantom comprised of slices of chicken breast tissue and the absorbing object made of silicon rubber. The imaging capability of the system is investigated as a function of the thickness of the tissue sample. By irradiating the absorber directly with a short pulsed laser beam, the influence of changes in the stress wave profile on the detected signal is monitored. Finally, preliminary experiments imaging buried, absorbing objects in tissue are carried out demonstrating the feasibility of this imaging method.

Original languageEnglish (US)
Pages (from-to)303-309
Number of pages7
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume3601
StatePublished - 1999
Externally publishedYes
EventProceedings of the 1999 Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical - San Jose, CA, USA
Duration: Jan 24 1999Jan 27 1999

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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