Pheochromocytoma: 20 years of improving surgical care

Tarin C. Worrest, Erin Gilbert, Brett Sheppard

Research output: Contribution to journalArticle

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Abstract

Background: Laparoscopic adrenalectomy is now the standard for pheochromocytoma. We report two decades of institutional experience with pheochromocytoma adrenalectomy. Methods: A retrospective review was undertaken of pheochromocytoma adrenalectomy patients between 1997 and 2017. Clinical variables and postoperative complications were recorded. Patients were divided into quartiles for analysis: group 1 from 1997 to 2001, group 2 from 2002 to 2006, group 3 from 2007 to 2011, and group 4 from 2012 to 2017. Results: Eighty-two pheochromocytoma adrenalectomies were identified. The percentage of laparoscopic adrenalectomies increased over time: 60% in group 1–87.5% in group 4 (p = 0.03). The average tumor size decreased: 6.4 cm (2.8–14.3 cm) in group 1–4.6 cm (1.2–7.8 cm) in group 4 (p = 0.03). ICU utilization decreased from 80% to 40.6% (p = 0.03) and length of stay decreased from 7.2 days to 2.7 days (p = 0.005). Clavien-Dindo grade>3 complications did not differ between the quartiles (p = 0.08). Conclusion: Pheochromocytoma care has evolved from more open procedures with standard postoperative ICU stay to a laparoscopic resection with targeted ICU care and decreased length of stay. As experience with laparoscopic adrenalectomy increases, patient outcomes improve.

Original languageEnglish (US)
JournalAmerican journal of surgery
DOIs
StatePublished - Jan 1 2019

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Adrenalectomy
Pheochromocytoma
Length of Stay
Neoplasms

ASJC Scopus subject areas

  • Surgery

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Pheochromocytoma : 20 years of improving surgical care. / Worrest, Tarin C.; Gilbert, Erin; Sheppard, Brett.

In: American journal of surgery, 01.01.2019.

Research output: Contribution to journalArticle

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abstract = "Background: Laparoscopic adrenalectomy is now the standard for pheochromocytoma. We report two decades of institutional experience with pheochromocytoma adrenalectomy. Methods: A retrospective review was undertaken of pheochromocytoma adrenalectomy patients between 1997 and 2017. Clinical variables and postoperative complications were recorded. Patients were divided into quartiles for analysis: group 1 from 1997 to 2001, group 2 from 2002 to 2006, group 3 from 2007 to 2011, and group 4 from 2012 to 2017. Results: Eighty-two pheochromocytoma adrenalectomies were identified. The percentage of laparoscopic adrenalectomies increased over time: 60{\%} in group 1–87.5{\%} in group 4 (p = 0.03). The average tumor size decreased: 6.4 cm (2.8–14.3 cm) in group 1–4.6 cm (1.2–7.8 cm) in group 4 (p = 0.03). ICU utilization decreased from 80{\%} to 40.6{\%} (p = 0.03) and length of stay decreased from 7.2 days to 2.7 days (p = 0.005). Clavien-Dindo grade>3 complications did not differ between the quartiles (p = 0.08). Conclusion: Pheochromocytoma care has evolved from more open procedures with standard postoperative ICU stay to a laparoscopic resection with targeted ICU care and decreased length of stay. As experience with laparoscopic adrenalectomy increases, patient outcomes improve.",
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