Phenotypic profiling of cognitive impairment risk among patients with heart failure: A literature review of the usefulness of cardiac-related variables

Corrine Y. Jurgens, Kenneth M. Faulkner, Christopher Lee

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: Mild cognitive impairment among patients with heart failure can be subtle. Heart failure-related variables such as ejection fraction, low systolic blood pressure and functional status are reportedly associated with cognitive impairment among heart failure patients. The purpose of this literature review was to examine the value of cardiac variables commonly assessed during heart failure-related hospitalizations for a phenotypic profile of the risk of cognitive impairment. Method: A literature review of primary research studies was conducted. Electronic databases (PubMed and CINAHL) were searched using the keywords heart failure, blood pressure, ejection fraction, functional status, and B-type natriuretic peptide (BNP) in combination with the terms cognition, cognitive function, cognitive dysfunction, and cognitive impairment. Results: Thirty-seven studies met the inclusion criteria. Evidence supports the potential utility of lower ejection fraction, lower blood pressure and functional status and elevated B-type natriuretic peptide as a phenotypic profile for an increased risk of cognitive impairment. Implications: If the risk for cognitive impairment is suspected, specific evaluations of cognition can be performed. For community-dwelling heart failure patients with mild cognitive impairment, more intense interventions to support selfcare, increased family involvement and more frequent follow up may be necessary.

Original languageEnglish (US)
Pages (from-to)109-131
Number of pages23
JournalEuropean Journal of Cardiovascular Nursing
Volume12
Issue number2
DOIs
StatePublished - Apr 2013

Fingerprint

Heart Failure
Cognition
Brain Natriuretic Peptide
Blood Pressure
Independent Living
Cognitive Dysfunction
PubMed
Hypotension
Hospitalization
Databases
Research

Keywords

  • cardiac-related variables
  • cognitive impairment
  • Heart failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing
  • Medical–Surgical

Cite this

Phenotypic profiling of cognitive impairment risk among patients with heart failure : A literature review of the usefulness of cardiac-related variables. / Jurgens, Corrine Y.; Faulkner, Kenneth M.; Lee, Christopher.

In: European Journal of Cardiovascular Nursing, Vol. 12, No. 2, 04.2013, p. 109-131.

Research output: Contribution to journalArticle

@article{2a3bbadd02e34e319bb7fc1dd1ccd162,
title = "Phenotypic profiling of cognitive impairment risk among patients with heart failure: A literature review of the usefulness of cardiac-related variables",
abstract = "Background: Mild cognitive impairment among patients with heart failure can be subtle. Heart failure-related variables such as ejection fraction, low systolic blood pressure and functional status are reportedly associated with cognitive impairment among heart failure patients. The purpose of this literature review was to examine the value of cardiac variables commonly assessed during heart failure-related hospitalizations for a phenotypic profile of the risk of cognitive impairment. Method: A literature review of primary research studies was conducted. Electronic databases (PubMed and CINAHL) were searched using the keywords heart failure, blood pressure, ejection fraction, functional status, and B-type natriuretic peptide (BNP) in combination with the terms cognition, cognitive function, cognitive dysfunction, and cognitive impairment. Results: Thirty-seven studies met the inclusion criteria. Evidence supports the potential utility of lower ejection fraction, lower blood pressure and functional status and elevated B-type natriuretic peptide as a phenotypic profile for an increased risk of cognitive impairment. Implications: If the risk for cognitive impairment is suspected, specific evaluations of cognition can be performed. For community-dwelling heart failure patients with mild cognitive impairment, more intense interventions to support selfcare, increased family involvement and more frequent follow up may be necessary.",
keywords = "cardiac-related variables, cognitive impairment, Heart failure",
author = "Jurgens, {Corrine Y.} and Faulkner, {Kenneth M.} and Christopher Lee",
year = "2013",
month = "4",
doi = "10.1177/1474515112470046",
language = "English (US)",
volume = "12",
pages = "109--131",
journal = "European Journal of Cardiovascular Nursing",
issn = "1474-5151",
publisher = "Elsevier",
number = "2",

}

TY - JOUR

T1 - Phenotypic profiling of cognitive impairment risk among patients with heart failure

T2 - A literature review of the usefulness of cardiac-related variables

AU - Jurgens, Corrine Y.

AU - Faulkner, Kenneth M.

AU - Lee, Christopher

PY - 2013/4

Y1 - 2013/4

N2 - Background: Mild cognitive impairment among patients with heart failure can be subtle. Heart failure-related variables such as ejection fraction, low systolic blood pressure and functional status are reportedly associated with cognitive impairment among heart failure patients. The purpose of this literature review was to examine the value of cardiac variables commonly assessed during heart failure-related hospitalizations for a phenotypic profile of the risk of cognitive impairment. Method: A literature review of primary research studies was conducted. Electronic databases (PubMed and CINAHL) were searched using the keywords heart failure, blood pressure, ejection fraction, functional status, and B-type natriuretic peptide (BNP) in combination with the terms cognition, cognitive function, cognitive dysfunction, and cognitive impairment. Results: Thirty-seven studies met the inclusion criteria. Evidence supports the potential utility of lower ejection fraction, lower blood pressure and functional status and elevated B-type natriuretic peptide as a phenotypic profile for an increased risk of cognitive impairment. Implications: If the risk for cognitive impairment is suspected, specific evaluations of cognition can be performed. For community-dwelling heart failure patients with mild cognitive impairment, more intense interventions to support selfcare, increased family involvement and more frequent follow up may be necessary.

AB - Background: Mild cognitive impairment among patients with heart failure can be subtle. Heart failure-related variables such as ejection fraction, low systolic blood pressure and functional status are reportedly associated with cognitive impairment among heart failure patients. The purpose of this literature review was to examine the value of cardiac variables commonly assessed during heart failure-related hospitalizations for a phenotypic profile of the risk of cognitive impairment. Method: A literature review of primary research studies was conducted. Electronic databases (PubMed and CINAHL) were searched using the keywords heart failure, blood pressure, ejection fraction, functional status, and B-type natriuretic peptide (BNP) in combination with the terms cognition, cognitive function, cognitive dysfunction, and cognitive impairment. Results: Thirty-seven studies met the inclusion criteria. Evidence supports the potential utility of lower ejection fraction, lower blood pressure and functional status and elevated B-type natriuretic peptide as a phenotypic profile for an increased risk of cognitive impairment. Implications: If the risk for cognitive impairment is suspected, specific evaluations of cognition can be performed. For community-dwelling heart failure patients with mild cognitive impairment, more intense interventions to support selfcare, increased family involvement and more frequent follow up may be necessary.

KW - cardiac-related variables

KW - cognitive impairment

KW - Heart failure

UR - http://www.scopus.com/inward/record.url?scp=84875199384&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84875199384&partnerID=8YFLogxK

U2 - 10.1177/1474515112470046

DO - 10.1177/1474515112470046

M3 - Article

C2 - 23303768

AN - SCOPUS:84875199384

VL - 12

SP - 109

EP - 131

JO - European Journal of Cardiovascular Nursing

JF - European Journal of Cardiovascular Nursing

SN - 1474-5151

IS - 2

ER -