Phase-stabilized complex-decorrelation angiography

Xiang Wei; Tristan T. Hormel; Yali Jia

doi:10.1364/BOE.420503

Phase-stabilized complex-decorrelation angiography

Xiang Wei, Tristan T. Hormel, Yali Jia

Ophthalmology

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

In this study, we developed a novel phase-stabilized complex-decorrelation (PSCD) optical coherence tomography (OCT) angiography (OCTA) method that can generate high quality OCTA images. This method has been validated using three different types of OCT systems and compared with conventional complex- and amplitude-based OCTA algorithms. Our results suggest that in combination with a pre-processing phase stabilization method, the PSCD method is insensitive to bulk motion phase shifts, less dependent on OCT reflectance than conventional complex methods and demonstrates extended dynamic range of flow signal, in contrast to other two methods.

Original language	English (US)
Pages (from-to)	2419-2431
Number of pages	13
Journal	Biomedical Optics Express
Volume	12
Issue number	4
DOIs	https://doi.org/10.1364/BOE.420503
State	Published - Apr 2021

ASJC Scopus subject areas

Biotechnology
Atomic and Molecular Physics, and Optics

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title = "Phase-stabilized complex-decorrelation angiography",

abstract = "In this study, we developed a novel phase-stabilized complex-decorrelation (PSCD) optical coherence tomography (OCT) angiography (OCTA) method that can generate high quality OCTA images. This method has been validated using three different types of OCT systems and compared with conventional complex- and amplitude-based OCTA algorithms. Our results suggest that in combination with a pre-processing phase stabilization method, the PSCD method is insensitive to bulk motion phase shifts, less dependent on OCT reflectance than conventional complex methods and demonstrates extended dynamic range of flow signal, in contrast to other two methods.",

author = "Xiang Wei and Hormel, {Tristan T.} and Yali Jia",

note = "Publisher Copyright: {\textcopyright} 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.",

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AU - Wei, Xiang

AU - Hormel, Tristan T.

AU - Jia, Yali

PY - 2021/4

Y1 - 2021/4

N2 - In this study, we developed a novel phase-stabilized complex-decorrelation (PSCD) optical coherence tomography (OCT) angiography (OCTA) method that can generate high quality OCTA images. This method has been validated using three different types of OCT systems and compared with conventional complex- and amplitude-based OCTA algorithms. Our results suggest that in combination with a pre-processing phase stabilization method, the PSCD method is insensitive to bulk motion phase shifts, less dependent on OCT reflectance than conventional complex methods and demonstrates extended dynamic range of flow signal, in contrast to other two methods.

AB - In this study, we developed a novel phase-stabilized complex-decorrelation (PSCD) optical coherence tomography (OCT) angiography (OCTA) method that can generate high quality OCTA images. This method has been validated using three different types of OCT systems and compared with conventional complex- and amplitude-based OCTA algorithms. Our results suggest that in combination with a pre-processing phase stabilization method, the PSCD method is insensitive to bulk motion phase shifts, less dependent on OCT reflectance than conventional complex methods and demonstrates extended dynamic range of flow signal, in contrast to other two methods.

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Phase-stabilized complex-decorrelation angiography

Abstract

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