Pharmaconutrition Review

Physiological Mechanisms

Robert Martindale, Aaron F. Heneghan, Christy M. Lawson, Paul E. Wischmeyer, Rosemary A. Kozar, Kenneth A. Kudsk

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The search to improve outcomes in critically ill patients through nutrition support has steadily progressed over the past 4 decades. One current approach to this problem is the addition of specific nutrients as primary therapy to improve host defenses and improve the outcome of critically ill patients. The field is referred to as “pharmaconutrition,” with the hope of focusing investigations on each nutrient to understand its pharmacological effects on immune and clinical outcomes. The purpose of this review is to describe some of the known physiological mechanisms of pharmaconutrients such as glutamine, arginine, ω-3 fatty acids, and selenium.

Original languageEnglish (US)
Pages (from-to)51S-65S
JournalJournal of Parenteral and Enteral Nutrition
Volume37
DOIs
StatePublished - 2013
Externally publishedYes

Fingerprint

Critical Illness
Food
Selenium
Glutamine
Arginine
Fatty Acids
Pharmacology
Therapeutics

Keywords

  • immune modulation
  • immunonutrition
  • nutrition therapy
  • pharmaconutrition

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Martindale, R., Heneghan, A. F., Lawson, C. M., Wischmeyer, P. E., Kozar, R. A., & Kudsk, K. A. (2013). Pharmaconutrition Review: Physiological Mechanisms. Journal of Parenteral and Enteral Nutrition, 37, 51S-65S. https://doi.org/10.1177/0148607113493326

Pharmaconutrition Review : Physiological Mechanisms. / Martindale, Robert; Heneghan, Aaron F.; Lawson, Christy M.; Wischmeyer, Paul E.; Kozar, Rosemary A.; Kudsk, Kenneth A.

In: Journal of Parenteral and Enteral Nutrition, Vol. 37, 2013, p. 51S-65S.

Research output: Contribution to journalArticle

Martindale, R, Heneghan, AF, Lawson, CM, Wischmeyer, PE, Kozar, RA & Kudsk, KA 2013, 'Pharmaconutrition Review: Physiological Mechanisms', Journal of Parenteral and Enteral Nutrition, vol. 37, pp. 51S-65S. https://doi.org/10.1177/0148607113493326
Martindale, Robert ; Heneghan, Aaron F. ; Lawson, Christy M. ; Wischmeyer, Paul E. ; Kozar, Rosemary A. ; Kudsk, Kenneth A. / Pharmaconutrition Review : Physiological Mechanisms. In: Journal of Parenteral and Enteral Nutrition. 2013 ; Vol. 37. pp. 51S-65S.
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