PET-guided biopsy with needle navigation facilitates diagnosis of angiosarcoma in neurofibromatosis type 1

Yilun Koethe; Brigitte C. Widemann; Fouad Hajjar; Bradford J. Wood; Aradhana M. Venkatesan

doi:10.1002/pbc.24668

PET-guided biopsy with needle navigation facilitates diagnosis of angiosarcoma in neurofibromatosis type 1

Yilun Koethe, Brigitte C. Widemann, Fouad Hajjar, Bradford J. Wood, Aradhana M. Venkatesan

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Malignant degeneration frequently arises from preexisting plexiform neurofibroma in patients with neurofibromatosis type 1 (NF1). Image guided biopsy for diagnostic purposes, such as with CT guidance, can be technically challenging in these patients, as CT cannot distinguish malignant from benign areas within the same tumor. Navigation with multi-modality (PET, CT, and ultrasound) image fusion facilitated the successful biopsy and diagnosis of angiosarcoma arising from a pelvic neurofibroma in a patient with NF1. Successful targeting assisted treatment selection in this case. This novel navigation technique may facilitate the otherwise difficult diagnosis of malignancy in patients with NF1. Pediatr Blood Cancer 2013;60:E166-E169.

Original language	English (US)
Pages (from-to)	E166-E169
Journal	Pediatric Blood and Cancer
Volume	60
Issue number	12
DOIs	https://doi.org/10.1002/pbc.24668
State	Published - Dec 2013
Externally published	Yes

Keywords

FDG-PET
Image guided biopsy
Malignant peripheral neural sheath tumor
Neurofibromatosis type 1
Plexiform neurofibroma

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1002/pbc.24668

Cite this

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title = "PET-guided biopsy with needle navigation facilitates diagnosis of angiosarcoma in neurofibromatosis type 1",

abstract = "Malignant degeneration frequently arises from preexisting plexiform neurofibroma in patients with neurofibromatosis type 1 (NF1). Image guided biopsy for diagnostic purposes, such as with CT guidance, can be technically challenging in these patients, as CT cannot distinguish malignant from benign areas within the same tumor. Navigation with multi-modality (PET, CT, and ultrasound) image fusion facilitated the successful biopsy and diagnosis of angiosarcoma arising from a pelvic neurofibroma in a patient with NF1. Successful targeting assisted treatment selection in this case. This novel navigation technique may facilitate the otherwise difficult diagnosis of malignancy in patients with NF1. Pediatr Blood Cancer 2013;60:E166-E169.",

keywords = "FDG-PET, Image guided biopsy, Malignant peripheral neural sheath tumor, Neurofibromatosis type 1, Plexiform neurofibroma",

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AU - Koethe, Yilun

AU - Widemann, Brigitte C.

AU - Hajjar, Fouad

AU - Wood, Bradford J.

AU - Venkatesan, Aradhana M.

PY - 2013/12

Y1 - 2013/12

N2 - Malignant degeneration frequently arises from preexisting plexiform neurofibroma in patients with neurofibromatosis type 1 (NF1). Image guided biopsy for diagnostic purposes, such as with CT guidance, can be technically challenging in these patients, as CT cannot distinguish malignant from benign areas within the same tumor. Navigation with multi-modality (PET, CT, and ultrasound) image fusion facilitated the successful biopsy and diagnosis of angiosarcoma arising from a pelvic neurofibroma in a patient with NF1. Successful targeting assisted treatment selection in this case. This novel navigation technique may facilitate the otherwise difficult diagnosis of malignancy in patients with NF1. Pediatr Blood Cancer 2013;60:E166-E169.

AB - Malignant degeneration frequently arises from preexisting plexiform neurofibroma in patients with neurofibromatosis type 1 (NF1). Image guided biopsy for diagnostic purposes, such as with CT guidance, can be technically challenging in these patients, as CT cannot distinguish malignant from benign areas within the same tumor. Navigation with multi-modality (PET, CT, and ultrasound) image fusion facilitated the successful biopsy and diagnosis of angiosarcoma arising from a pelvic neurofibroma in a patient with NF1. Successful targeting assisted treatment selection in this case. This novel navigation technique may facilitate the otherwise difficult diagnosis of malignancy in patients with NF1. Pediatr Blood Cancer 2013;60:E166-E169.

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KW - Image guided biopsy

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KW - Neurofibromatosis type 1

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PET-guided biopsy with needle navigation facilitates diagnosis of angiosarcoma in neurofibromatosis type 1

Abstract

Keywords

ASJC Scopus subject areas

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