Personalized cancer therapy: A publicly available precision oncology resource

Katherine C. Kurnit, Ann M. Bailey, Jia Zeng, Amber M. Johnson, M. A. Shufean, Lauren Brusco, Beate C. Litzenburger, Nora S. Sanchez, Yekaterina B. Khotskaya, Vijaykumar Holla, Amy Simpson, Gordon Mills, John Mendelsohn, Elmer Bernstam, Kenna Shaw, Funda Meric-Bernstam

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

High-throughput genomic and molecular profiling of tumors is emerging as an important clinical approach. Molecular profiling is increasingly being used to guide cancer patient care, especially in advanced and incurable cancers. However, navigating the scientific literature to make evidence-based clinical decisions based on molecular profiling results is overwhelming for many oncology clinicians and researchers. The Personalized Cancer Therapy website (www. personalizedcancertherapy.org) was created to provide an online resource for clinicians and researchers to facilitate navigation of available data. Specifically, this resource can be used to help identify potential therapy options for patients harboring oncogenic genomic alterations. Herein, we describe how content on www.personalized cancertherapy.org is generated and maintained. We end with case scenarios to illustrate the clinical utility of the website. The goal of this publicly available resource is to provide easily accessible information to a broad oncology audience, as this may help ease the information retrieval burden facing participants in the precision oncology field. Cancer Res; 77(21); e123–6. 2017 AACR.

Original languageEnglish (US)
Pages (from-to)e123-e126
JournalCancer Research
Volume77
Issue number21
DOIs
StatePublished - Nov 1 2017
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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  • Cite this

    Kurnit, K. C., Bailey, A. M., Zeng, J., Johnson, A. M., Shufean, M. A., Brusco, L., Litzenburger, B. C., Sanchez, N. S., Khotskaya, Y. B., Holla, V., Simpson, A., Mills, G., Mendelsohn, J., Bernstam, E., Shaw, K., & Meric-Bernstam, F. (2017). Personalized cancer therapy: A publicly available precision oncology resource. Cancer Research, 77(21), e123-e126. https://doi.org/10.1158/0008-5472.CAN-17-0341