Persistent type IV hypersensitivity after cyanoacrylate closure of the great saphenous vein

Andrew D. Jones, Edward M. Boyle, R. Woltjer, Jason P. Jundt, Adam N. Williams

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

The VenaSeal (Medtronic, Minneapolis, Minn) cyanoacrylate closure system is a nonthermal technique for ablating saphenous veins using a proprietary n-butyl cyanoacrylate. One possible side effect is an allergic reaction to cyanoacrylate. We report the case of a 49-year-old woman treated with cyanoacrylate closure who developed a persistent type IV hypersensitivity reaction. The patient elected to have the vein excised, and the histologic features were consistent with a type IV hypersensitivity reaction.

Original languageEnglish (US)
Pages (from-to)372-374
Number of pages3
JournalJournal of Vascular Surgery Cases and Innovative Techniques
Volume5
Issue number3
DOIs
StatePublished - Sep 2019

Keywords

  • Allergic reaction
  • Endovenous ablation
  • Hypersensitivity
  • Varicose vein
  • VenaSeal

ASJC Scopus subject areas

  • Surgery
  • Cardiology and Cardiovascular Medicine

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