TY - JOUR
T1 - Persistent photosensitivity after allergic contact dermatitis to epoxy resin
AU - Kwok, Tiffany
AU - Rosen, Cheryl F.
AU - Storrs, Frances J.
AU - Lobel, Edmund
AU - DeKoven, Joel G.
PY - 2013
Y1 - 2013
N2 - Background: Persistent photosensitivity after allergic contact dermatitis (ACD) to epoxy resin has rarely been described. Objective: The aim of this study was to create awareness that ACD to epoxy may be a trigger for persistent photosensitivity. Methods: We present a series of 5 patientswho developed ACD to epoxy resin and later a photodistributed eczematous eruption when exposed to sunlight, with a documented decrease in minimal erythema dose to UVA and UVB. Results: The age of patients ranged from 34 to 71 years, and there were 3 men and 2 women. Each patient had occupational exposure to epoxy. Symptoms of epoxy ACD preceded photosensitivity by 5 months to 12 years in 3 cases and occurred simultaneously in 2 cases. Patch testing to epoxy resin was positive in all patients. Phototesting revealed a decreased minimal erythema dose to UVA and UVB in each of the 3 patients who were phototested. Photopatch testing was positive for epoxy resin in 1 of the 2 patients tested. All patients remained photosensitive for at least 2 years after diagnosis, with only 1 case of photosensitivity resolving with extended avoidance of epoxy. Conclusions: There is an association between ACD to epoxy resin and development of persistent photosensitivity. Possible mechanisms to explain the relationship between the 2 phenomena are discussed.
AB - Background: Persistent photosensitivity after allergic contact dermatitis (ACD) to epoxy resin has rarely been described. Objective: The aim of this study was to create awareness that ACD to epoxy may be a trigger for persistent photosensitivity. Methods: We present a series of 5 patientswho developed ACD to epoxy resin and later a photodistributed eczematous eruption when exposed to sunlight, with a documented decrease in minimal erythema dose to UVA and UVB. Results: The age of patients ranged from 34 to 71 years, and there were 3 men and 2 women. Each patient had occupational exposure to epoxy. Symptoms of epoxy ACD preceded photosensitivity by 5 months to 12 years in 3 cases and occurred simultaneously in 2 cases. Patch testing to epoxy resin was positive in all patients. Phototesting revealed a decreased minimal erythema dose to UVA and UVB in each of the 3 patients who were phototested. Photopatch testing was positive for epoxy resin in 1 of the 2 patients tested. All patients remained photosensitive for at least 2 years after diagnosis, with only 1 case of photosensitivity resolving with extended avoidance of epoxy. Conclusions: There is an association between ACD to epoxy resin and development of persistent photosensitivity. Possible mechanisms to explain the relationship between the 2 phenomena are discussed.
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U2 - 10.1097/DER.0b013e31828afadf
DO - 10.1097/DER.0b013e31828afadf
M3 - Article
C2 - 23665827
AN - SCOPUS:84881347569
SN - 1710-3568
VL - 24
SP - 124
EP - 130
JO - Dermatitis : contact, atopic, occupational, drug
JF - Dermatitis : contact, atopic, occupational, drug
IS - 3
ER -