TY - JOUR
T1 - Peripseudophakic Membrane
T2 - Pathologic Features
AU - Pavilack, Mark A.
AU - Foster, C. Stephen
AU - Kowal, Vera O.
AU - Dutt, James E.
AU - Albert, Daniel M.
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 1993/2
Y1 - 1993/2
N2 - A 70-year-old woman underwent anterior segment reconstruction with repeated penetrating keratoplasty for visual rehabilitation. On removal of the failed keratoplasty button, the posterior chamber intraocular lens was found to be encased in a dense fibrous membrane that almost totally obliterated the anterior and posterior chambers of the eye. Anterior segment reconstruction included excision of the fibrous membrane, removal of the intraocular lens, iridoplasty, gonioplasty, anterior vitrectomy, and repeated penetrating keratoplasty. Recognition of fibrous tissue that extended through each of the four positioning holes of the optic of the lens implant and its transection was essential in avoiding complications during removal of the intraocular lens. Histopathologic and ultrastructural examination of the excised membrane revealed areas of metaplastic lens epithelium and fibrous scar tissue. This study, using immunofluorescence, is the first, to our knowledge, to characterize the specific collagenous components of a peripseudophakic membrane.
AB - A 70-year-old woman underwent anterior segment reconstruction with repeated penetrating keratoplasty for visual rehabilitation. On removal of the failed keratoplasty button, the posterior chamber intraocular lens was found to be encased in a dense fibrous membrane that almost totally obliterated the anterior and posterior chambers of the eye. Anterior segment reconstruction included excision of the fibrous membrane, removal of the intraocular lens, iridoplasty, gonioplasty, anterior vitrectomy, and repeated penetrating keratoplasty. Recognition of fibrous tissue that extended through each of the four positioning holes of the optic of the lens implant and its transection was essential in avoiding complications during removal of the intraocular lens. Histopathologic and ultrastructural examination of the excised membrane revealed areas of metaplastic lens epithelium and fibrous scar tissue. This study, using immunofluorescence, is the first, to our knowledge, to characterize the specific collagenous components of a peripseudophakic membrane.
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U2 - 10.1001/archopht.1993.01090020094031
DO - 10.1001/archopht.1993.01090020094031
M3 - Article
C2 - 8431163
AN - SCOPUS:0027475161
SN - 0003-9950
VL - 111
SP - 240
EP - 244
JO - Archives of ophthalmology
JF - Archives of ophthalmology
IS - 2
ER -