Perinatal bacterial infection: An update

T. J. Yeagley, Jorge Tolosa, V. K. Bhutani

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

This article reviews the current trends in the evaluation and management of bacterial infection involving the uterus, placenta, membranes, amniotic fluid, and fetus occurring near the time of birth. The discussion includes information regarding risk, incidence, pathophysiology, bedside diagnosis, interventional options including antibiotics, corticosteroids, fetal monitoring, and delivery, and possible preventive measures which affect the outcome. The adequate evaluation and management of perinatal infection requires a team approach with obstetricians and pediatricians. Clinical screening is useful in developing the diagnosis, but amniotic fluid evaluation remains the proposed gold standard. The role of cytokines is becoming increasingly important, as is seen in the association of IL-6 with positive amniotic fluid cultures and periventricular leukomalacia. Prompt recognition and management of the pregnancy affected by infection can improve perinatal outcomes. A management protocol is presented to help structure the approach to suspected infection. Premature delivery due to perinatal infection may be preventable.

Original languageEnglish (US)
Pages (from-to)841-848
Number of pages8
JournalIndian Journal of Pediatrics
Volume65
Issue number6
StatePublished - 1998
Externally publishedYes

Fingerprint

Bacterial Infections
Amniotic Fluid
Infection
Periventricular Leukomalacia
Fetal Monitoring
Placenta
Uterus
Interleukin-6
Adrenal Cortex Hormones
Fetus
Parturition
Cytokines
Anti-Bacterial Agents
Pregnancy
Membranes
Incidence

Keywords

  • Chorioamnionitis
  • Intraamniotic infection
  • Pregnancy complications

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Yeagley, T. J., Tolosa, J., & Bhutani, V. K. (1998). Perinatal bacterial infection: An update. Indian Journal of Pediatrics, 65(6), 841-848.

Perinatal bacterial infection : An update. / Yeagley, T. J.; Tolosa, Jorge; Bhutani, V. K.

In: Indian Journal of Pediatrics, Vol. 65, No. 6, 1998, p. 841-848.

Research output: Contribution to journalArticle

Yeagley, TJ, Tolosa, J & Bhutani, VK 1998, 'Perinatal bacterial infection: An update', Indian Journal of Pediatrics, vol. 65, no. 6, pp. 841-848.
Yeagley, T. J. ; Tolosa, Jorge ; Bhutani, V. K. / Perinatal bacterial infection : An update. In: Indian Journal of Pediatrics. 1998 ; Vol. 65, No. 6. pp. 841-848.
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