Performance and reliability of the CPB/ECMO initiative forward lines casualty management system

Fernando Casas, Andrew Reeves, David Dudzinski, Stephan Weber, Markus Lorenz, Masatoshi Akiyama, Keiji Kamohara, Michael Kopcak, Yoshio Ootaki, Firas Zahr, Martin Sinkewich, Robert Foster, Kiyotaka Fukamachi, William A. Smith

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The Cleveland Clinic Foundation CPB/ECMO Initiative Forward Casualty Management System is an economical, compact, transportable, disposable system designed to permit a rapid expansion of trauma management services requiring cardiopulmonary bypass (CPB) or extracorporeal membrane oxygenation (ECMO) pulmonary support. The system, composed of a rotary blood pump, a pump motor driver, and an electronic control console as the blood pumping subsystem, also includes commonly used compatible commercial oxygenators, venous reservoirs, and cannulae. In vitro durability testing accumulated over 100 hours without failure. In vivo reliability was tested in 10 calves under general anesthesia during 6 hours of CPB and ECMO under full heparinization at nominal operating conditions of 4-5 l/min and 2-4 l/min blood flow respectively, and mean arterial pressures between 65 and 100 mm Hg. A mean time to failure of 57 hours was reached during the animal series. Results of these test series demonstrated that this system has the capability to reliably operate during a 6-hour conventional CPB or ECMO procedure, while providing flexibility and ease of use for the operator.

Original languageEnglish (US)
Pages (from-to)681-685
Number of pages5
JournalASAIO Journal
Volume51
Issue number6
DOIs
StatePublished - Nov 1 2005

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

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    Casas, F., Reeves, A., Dudzinski, D., Weber, S., Lorenz, M., Akiyama, M., Kamohara, K., Kopcak, M., Ootaki, Y., Zahr, F., Sinkewich, M., Foster, R., Fukamachi, K., & Smith, W. A. (2005). Performance and reliability of the CPB/ECMO initiative forward lines casualty management system. ASAIO Journal, 51(6), 681-685. https://doi.org/10.1097/01.mat.0000182472.63808.b9