Percutaneous transcatheter aortic disc valve prosthesis implantation: A feasibility study

Jan Šochman, Jan H. Peregrin, Dušan Pavčnik, Hans Timmermans, Josef Rösch

Research output: Contribution to journalArticle

51 Scopus citations

Abstract

Purpose: Over the past 30 years there have been experimental efforts at catheter-based management of aortic valve regurgitation with the idea of extending treatment to nonsurgical candidates. A new catheter-based aortic valve design is described. Methods: The new catheter-delivered valve consists of a stent-based valve cage with locking mechanism and a prosthetic flexible tilting valve disc. The valve cage is delivered first followed by deployment and locking of the disc. In acute experiments, valve implantation was done in four dogs. Results: Valve implantation was successful in all four animals. The implanted valve functioned well for the duration of the experiments (up to 3 hr). Conclusion: The study showed the implantation feasibility and short-term function of the tested catheter-based aortic disc valve. Further experimental studies are warranted.

Original languageEnglish (US)
Pages (from-to)384-388
Number of pages5
JournalCardiovascular and interventional radiology
Volume23
Issue number5
DOIs
StatePublished - Dec 4 2000

Keywords

  • Aortic regurgitation
  • Catheterization technique
  • Disc valve prosthesis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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