Percutaneous bioprosthetic venous valve: A long-term study in sheep

Dusan Pavcnik; Barry T. Uchida; Hans A. Timmermans; Christopher L. Corless; Michael O'Hara; Naoyuki Toyota; Gregory L. Moneta; Frederick S. Keller; Josef Rösch

doi:10.1067/mva.2002.118825

Percutaneous bioprosthetic venous valve: A long-term study in sheep

Dusan Pavcnik, Barry T. Uchida, Hans A. Timmermans, Christopher L. Corless, Michael O'Hara, Naoyuki Toyota, Gregory L. Moneta, Frederick S. Keller, Josef Rösch

Research output: Contribution to journal › Article › peer-review

92 Scopus citations

Abstract

A long-term evaluation of a new percutaneously placed bioprosthetic, bicuspid venous valve (BVV) consisting of a square stent and small intestinal submucosa (SIS) covering was performed in 12 sheep. Of 26 BVVs placed into the jugular veins, 25 exhibited good valve function on immediate venography and 22 on venograms obtained before the sheep were killed. Gross and histologic examination results demonstrated incorporation of remodeled and endothelialized SIS BVVs into the vein wall. Slight to moderate leaflet thickening was found mostly at their bases. Percutaneously placed SIS BVV is a promising one-way, competent valve that resists venous back-pressure while allowing forward flow.

Original language	English (US)
Pages (from-to)	598-602
Number of pages	5
Journal	Journal of vascular surgery
Volume	35
Issue number	3
DOIs	https://doi.org/10.1067/mva.2002.118825
State	Published - Mar 2002

ASJC Scopus subject areas

Surgery
Cardiology and Cardiovascular Medicine

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title = "Percutaneous bioprosthetic venous valve: A long-term study in sheep",

abstract = "A long-term evaluation of a new percutaneously placed bioprosthetic, bicuspid venous valve (BVV) consisting of a square stent and small intestinal submucosa (SIS) covering was performed in 12 sheep. Of 26 BVVs placed into the jugular veins, 25 exhibited good valve function on immediate venography and 22 on venograms obtained before the sheep were killed. Gross and histologic examination results demonstrated incorporation of remodeled and endothelialized SIS BVVs into the vein wall. Slight to moderate leaflet thickening was found mostly at their bases. Percutaneously placed SIS BVV is a promising one-way, competent valve that resists venous back-pressure while allowing forward flow.",

author = "Dusan Pavcnik and Uchida, {Barry T.} and Timmermans, {Hans A.} and Corless, {Christopher L.} and Michael O'Hara and Naoyuki Toyota and Moneta, {Gregory L.} and Keller, {Frederick S.} and Josef R{\"o}sch",

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doi = "10.1067/mva.2002.118825",

language = "English (US)",

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journal = "Journal of vascular surgery",

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AU - Pavcnik, Dusan

AU - Uchida, Barry T.

AU - Timmermans, Hans A.

AU - Corless, Christopher L.

AU - O'Hara, Michael

AU - Toyota, Naoyuki

AU - Moneta, Gregory L.

AU - Keller, Frederick S.

AU - Rösch, Josef

N1 - Funding Information: Supported in part by a grant from Cook Inc.

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AB - A long-term evaluation of a new percutaneously placed bioprosthetic, bicuspid venous valve (BVV) consisting of a square stent and small intestinal submucosa (SIS) covering was performed in 12 sheep. Of 26 BVVs placed into the jugular veins, 25 exhibited good valve function on immediate venography and 22 on venograms obtained before the sheep were killed. Gross and histologic examination results demonstrated incorporation of remodeled and endothelialized SIS BVVs into the vein wall. Slight to moderate leaflet thickening was found mostly at their bases. Percutaneously placed SIS BVV is a promising one-way, competent valve that resists venous back-pressure while allowing forward flow.

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Percutaneous bioprosthetic venous valve: A long-term study in sheep

Abstract

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