TY - JOUR
T1 - Pediatric research priorities in healthcare-associated infections and antimicrobial stewardship
AU - Coffin, Susan E.
AU - Abanyie, Francisca
AU - Bryant, Kristina
AU - Cantey, Joseph
AU - Fiore, Anthony
AU - Fritz, Stephanie
AU - Guzman-Cottrill, Judith
AU - Hersh, Adam L.
AU - Huskins, W. Charles
AU - Kociolek, Larry K.
AU - Kronman, Matthew
AU - Lautenbach, Ebbing
AU - Lee, Grace
AU - Linam, Matthew
AU - Logan, Latania K.
AU - Milstone, Aaron
AU - Newland, Jason
AU - Nyquist, A. Christine
AU - Palazzi, Debra L.
AU - Patel, Sameer
AU - Puopolo, Karen
AU - Reddy, Sujan C.
AU - Saiman, Lisa
AU - Sandora, Thomas
AU - Shane, Andi L.
AU - Smith, Michael
AU - Tamma, Pranita D.
AU - Zaoutis, Theoklis
AU - Zerr, Danielle
AU - Gerber, Jeffrey S.
N1 - Publisher Copyright:
© 2020 The Author(s). Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America.
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020
Y1 - 2020
N2 - Objective: To develop a pediatric research agenda focused on pediatric healthcare-associated infections and antimicrobial stewardship topics that will yield the highest impact on child health. Participants: The study included 26 geographically diverse adult and pediatric infectious diseases clinicians with expertise in healthcare-associated infection prevention and/or antimicrobial stewardship (topic identification and ranking of priorities), as well as members of the Division of Healthcare Quality and Promotion at the Centers for Disease Control and Prevention (topic identification). Methods: Using a modified Delphi approach, expert recommendations were generated through an iterative process for identifying pediatric research priorities in healthcare associated infection prevention and antimicrobial stewardship. The multistep, 7-month process included a literature review, interactive teleconferences, web-based surveys, and 2 in-person meetings. Results: A final list of 12 high-priority research topics were generated in the 2 domains. High-priority healthcare-associated infection topics included judicious testing for Clostridioides difficile infection, chlorhexidine (CHG) bathing, measuring and preventing hospital-onset bloodstream infection rates, surgical site infection prevention, surveillance and prevention of multidrug resistant gram-negative rod infections. Antimicrobial stewardship topics included β-lactam allergy de-labeling, judicious use of perioperative antibiotics, intravenous to oral conversion of antimicrobial therapy, developing a patient-level "harm index"for antibiotic exposure, and benchmarking and or peer comparison of antibiotic use for common inpatient conditions. Conclusions: We identified 6 healthcare-associated infection topics and 6 antimicrobial stewardship topics as potentially high-impact targets for pediatric research.
AB - Objective: To develop a pediatric research agenda focused on pediatric healthcare-associated infections and antimicrobial stewardship topics that will yield the highest impact on child health. Participants: The study included 26 geographically diverse adult and pediatric infectious diseases clinicians with expertise in healthcare-associated infection prevention and/or antimicrobial stewardship (topic identification and ranking of priorities), as well as members of the Division of Healthcare Quality and Promotion at the Centers for Disease Control and Prevention (topic identification). Methods: Using a modified Delphi approach, expert recommendations were generated through an iterative process for identifying pediatric research priorities in healthcare associated infection prevention and antimicrobial stewardship. The multistep, 7-month process included a literature review, interactive teleconferences, web-based surveys, and 2 in-person meetings. Results: A final list of 12 high-priority research topics were generated in the 2 domains. High-priority healthcare-associated infection topics included judicious testing for Clostridioides difficile infection, chlorhexidine (CHG) bathing, measuring and preventing hospital-onset bloodstream infection rates, surgical site infection prevention, surveillance and prevention of multidrug resistant gram-negative rod infections. Antimicrobial stewardship topics included β-lactam allergy de-labeling, judicious use of perioperative antibiotics, intravenous to oral conversion of antimicrobial therapy, developing a patient-level "harm index"for antibiotic exposure, and benchmarking and or peer comparison of antibiotic use for common inpatient conditions. Conclusions: We identified 6 healthcare-associated infection topics and 6 antimicrobial stewardship topics as potentially high-impact targets for pediatric research.
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U2 - 10.1017/ice.2020.1267
DO - 10.1017/ice.2020.1267
M3 - Article
C2 - 33239122
AN - SCOPUS:85096867421
JO - Infection Control and Hospital Epidemiology
JF - Infection Control and Hospital Epidemiology
SN - 0899-823X
ER -