TY - JOUR
T1 - Pavlovian conditioning with ethanol and lithium
T2 - Effects on heart rate and taste aversion in rats
AU - Wilkin, Lawrence D.
AU - Cunningham, Christopher L.
AU - Fitzgerald, Robert D.
PY - 1982/10
Y1 - 1982/10
N2 - 20 female albino Simonsen rats received paired injections of either ethanol or saline as the CS and LiCl as the UCS in a Pavlovian differential conditioning paradigm. LiCl evoked a large deceleration in heart rate (80-200 beats/min) as a UCR. As a result of 10 conditioning trials, the substance paired with LiCl elicited a lower average heart rate than that elicited by the unpaired substance. Moreover, Ss that received ethanol-LiCl injections subsequently were more averse to the taste of ethanol than Ss receiving saline-LiCl pairings. However, there were no differences in ethanol's ability to serve as the UCS to induce an aversion to a novel flavor solution (i.e., the Avfail phenomenon was not observed). The overall pattern of results underscores the value of using multiple indexes of learning in drug-drug conditioning paradigms. (21 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved).
AB - 20 female albino Simonsen rats received paired injections of either ethanol or saline as the CS and LiCl as the UCS in a Pavlovian differential conditioning paradigm. LiCl evoked a large deceleration in heart rate (80-200 beats/min) as a UCR. As a result of 10 conditioning trials, the substance paired with LiCl elicited a lower average heart rate than that elicited by the unpaired substance. Moreover, Ss that received ethanol-LiCl injections subsequently were more averse to the taste of ethanol than Ss receiving saline-LiCl pairings. However, there were no differences in ethanol's ability to serve as the UCS to induce an aversion to a novel flavor solution (i.e., the Avfail phenomenon was not observed). The overall pattern of results underscores the value of using multiple indexes of learning in drug-drug conditioning paradigms. (21 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved).
KW - ethanol paired with lithium, heart rate &
KW - taste aversion, female rats
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U2 - 10.1037/h0077924
DO - 10.1037/h0077924
M3 - Article
C2 - 6292269
AN - SCOPUS:0020199457
SN - 0021-9940
VL - 96
SP - 781
EP - 790
JO - Journal of Comparative and Physiological Psychology
JF - Journal of Comparative and Physiological Psychology
IS - 5
ER -