Abstract
Background: The impact of melanoma genetic testing and counseling on photoprotective behaviors is unknown. Objective: To determine if genetic testing and counseling alter compliance with photoprotection recommendations. Methods: Reported use of sunscreen, protective clothing, and sun avoidance by 59 members of CDKN2A/p16-mutation positive pedigrees was assessed as a function of mutation status and melanoma history, before, immediately after, and 1 month following test reporting. Results: Intentions to practice all photoprotective behaviors increased in all participant groups (P < .0001). At 1 month, 33% of participants reported the adoption of a new photoprotective behavior. Subpopulation analyses identified different patterns of change in photoprotection relative to baseline (P < .005), with no net decline in any group. Limitations: This initial study of CDKN2A/p16 families is small and awaits replication in a larger sample. Conclusion: Melanoma genetic testing and counseling enhanced intentions to implement photoprotective strategies and did not result in reduced compliance in the CDKN2A/p16-subpopulation.
Original language | English (US) |
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Pages (from-to) | 745-757 |
Number of pages | 13 |
Journal | Journal of the American Academy of Dermatology |
Volume | 60 |
Issue number | 5 |
DOIs | |
State | Published - May 2009 |
Externally published | Yes |
Keywords
- CDKN2A
- UV exposure
- familial melanoma
- genetic counseling
- prevention
- sunscreen use
ASJC Scopus subject areas
- Dermatology