Patterns of photoprotection following CDKN2A/p16 genetic test reporting and counseling

Lisa G. Aspinwall, Samantha L. Leaf, Wendy Kohlmann, Erin R. Dola, Sancy Leachman

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background: The impact of melanoma genetic testing and counseling on photoprotective behaviors is unknown. Objective: To determine if genetic testing and counseling alter compliance with photoprotection recommendations. Methods: Reported use of sunscreen, protective clothing, and sun avoidance by 59 members of CDKN2A/p16-mutation positive pedigrees was assessed as a function of mutation status and melanoma history, before, immediately after, and 1 month following test reporting. Results: Intentions to practice all photoprotective behaviors increased in all participant groups (P <.0001). At 1 month, 33% of participants reported the adoption of a new photoprotective behavior. Subpopulation analyses identified different patterns of change in photoprotection relative to baseline (P <.005), with no net decline in any group. Limitations: This initial study of CDKN2A/p16 families is small and awaits replication in a larger sample. Conclusion: Melanoma genetic testing and counseling enhanced intentions to implement photoprotective strategies and did not result in reduced compliance in the CDKN2A/p16-subpopulation.

Original languageEnglish (US)
Pages (from-to)745-757
Number of pages13
JournalJournal of the American Academy of Dermatology
Volume60
Issue number5
DOIs
StatePublished - May 2009
Externally publishedYes

Fingerprint

Genetic Counseling
Genetic Testing
Counseling
Melanoma
Protective Clothing
Sunscreening Agents
Mutation
Solar System
Pedigree
Compliance

Keywords

  • CDKN2A
  • familial melanoma
  • genetic counseling
  • prevention
  • sunscreen use
  • UV exposure

ASJC Scopus subject areas

  • Dermatology

Cite this

Patterns of photoprotection following CDKN2A/p16 genetic test reporting and counseling. / Aspinwall, Lisa G.; Leaf, Samantha L.; Kohlmann, Wendy; Dola, Erin R.; Leachman, Sancy.

In: Journal of the American Academy of Dermatology, Vol. 60, No. 5, 05.2009, p. 745-757.

Research output: Contribution to journalArticle

Aspinwall, Lisa G. ; Leaf, Samantha L. ; Kohlmann, Wendy ; Dola, Erin R. ; Leachman, Sancy. / Patterns of photoprotection following CDKN2A/p16 genetic test reporting and counseling. In: Journal of the American Academy of Dermatology. 2009 ; Vol. 60, No. 5. pp. 745-757.
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