Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes

Rong Wang, Cary P. Gross, Ronald Maggiore, Stephanie Halene, Pamela R. Soulos, Azra Raza, Naomi Galili, Xiaomei Ma

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Little is known about how hypomethylating agents (HMAs) have been adopted into the treatment of myelodysplastic syndromes (MDS). We conducted a population-based study to assess the use of HMAs among 4416 MDS patients (age ≥66 years) who were diagnosed during 2001-2005 and followed up through the end of 2007. Multivariate logistic regression models were utilized to evaluate the role of various patient characteristics. 475 (10.8%) patients had received HMAs by 2007, with the proportion increasing over time. Patients who were white (odds ratio (OR)=0.66, 95% confidence interval (CI): 0.46-0.95), male (OR=1.47, 95% CI: 1.19-1.82), young (Ptrendtrend

Original languageEnglish (US)
Pages (from-to)904-908
Number of pages5
JournalLeukemia Research
Volume35
Issue number7
DOIs
StatePublished - Jul 2011
Externally publishedYes

Fingerprint

Myelodysplastic Syndromes
Logistic Models
Odds Ratio
Confidence Intervals
Population
Therapeutics

Keywords

  • Chemotherapy
  • Hematology-medical
  • Myelodysplastic syndromes
  • New agents

ASJC Scopus subject areas

  • Cancer Research
  • Hematology
  • Oncology

Cite this

Wang, R., Gross, C. P., Maggiore, R., Halene, S., Soulos, P. R., Raza, A., ... Ma, X. (2011). Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes. Leukemia Research, 35(7), 904-908. https://doi.org/10.1016/j.leukres.2010.10.007

Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes. / Wang, Rong; Gross, Cary P.; Maggiore, Ronald; Halene, Stephanie; Soulos, Pamela R.; Raza, Azra; Galili, Naomi; Ma, Xiaomei.

In: Leukemia Research, Vol. 35, No. 7, 07.2011, p. 904-908.

Research output: Contribution to journalArticle

Wang, R, Gross, CP, Maggiore, R, Halene, S, Soulos, PR, Raza, A, Galili, N & Ma, X 2011, 'Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes', Leukemia Research, vol. 35, no. 7, pp. 904-908. https://doi.org/10.1016/j.leukres.2010.10.007
Wang, Rong ; Gross, Cary P. ; Maggiore, Ronald ; Halene, Stephanie ; Soulos, Pamela R. ; Raza, Azra ; Galili, Naomi ; Ma, Xiaomei. / Pattern of hypomethylating agents use among elderly patients with myelodysplastic syndromes. In: Leukemia Research. 2011 ; Vol. 35, No. 7. pp. 904-908.
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