Pathophysiology of trigeminal neuralgia: New evidence from a trigeminal ganglion intraoperative microneurographic recording: Case report

Kim J. Burchiel, Thomas K. Baumann

Research output: Contribution to journalArticle

25 Scopus citations


The origin of trigeminal neuralgia (TN) appears to be vascular compression of the trigeminal nerve at the root entry zone; however, the physiological mechanism of this disorder remains uncertain. The authors obtained intraoperative microneurographic recordings from trigeminal ganglion neurons in a patient with TN immediately before percutaneous radiofrequency-induced gangliolysis. Their findings are consistent with the idea that the pain of TN is generated, at least in part, by an abnormal discharge within the peripheral nervous system.

Original languageEnglish (US)
Pages (from-to)872-873
Number of pages2
JournalJournal of neurosurgery
Issue number5
StatePublished - Nov 2004



  • Nerve action potential discharge
  • Pain
  • Peripheral nervous system
  • Trigeminal ganglion
  • Trigeminal neuralgia

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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