Paradoxical aversive conditioning with ethanol

Christopher Cunningham, James G. Linakis

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

In three experiments with hooded rats, paired injections of ethanol and lithium chloride produced an aversion to the taste of ethanol, yet reduced ethanol's potency as an unconditioned stimulus during subsequent taste aversion conditioning with saccharin (i.e., saccharin→ethanol). Two of the experiments were designed to test an associative "blocking" account of the latter finding. In each of these experiments, an attempt was made to extinguish the aversion conditioned to a potential blocking stimulus after ethanol-lithium pairings, but before saccharain-ethanol conditioning. Nonreinforced exposure to intraperitoneally mediated ethanol taste cues did not eliminate the detrimental effect of ethanol-lithium pairings on subsequent saccharin-ethanol conditioning (Experiment 2), whereas nonreinforced exposure to handling-injection cues did (Experiment 3), thus providing support for the associative blocking interpretation. Implications of these findings for chemical aversion therapy are discussed.

Original languageEnglish (US)
Pages (from-to)337-341
Number of pages5
JournalPharmacology, Biochemistry and Behavior
Volume12
Issue number3
DOIs
StatePublished - 1980

Fingerprint

Ethanol
Saccharin
Lithium
Experiments
Cues
Aversive Therapy
Lithium Chloride
Injections
Conditioning (Psychology)
Rats

Keywords

  • Aversion therapy
  • Blocking
  • Ethanol
  • Lithium chloride
  • Second-order conditioning
  • Taste aversion conditioning

ASJC Scopus subject areas

  • Biochemistry
  • Behavioral Neuroscience
  • Pharmacology

Cite this

Paradoxical aversive conditioning with ethanol. / Cunningham, Christopher; Linakis, James G.

In: Pharmacology, Biochemistry and Behavior, Vol. 12, No. 3, 1980, p. 337-341.

Research output: Contribution to journalArticle

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