Parachordoma

O. P. Sangueza, C. R. White

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Parachordomas are rare soft-tissue neoplasms that are histologically similar to chordomas. They typically develop adjacent to tendon, synovium, or osseous structures within extremities and present as slowly growing, locally destructive, lobulated neoplasms that are prone to recurrence if incompletely excised. We report a parachordoma occurring in the right middle finger of a 25-year-old man. The neoplasm had been present for 5 years, and the patient had sustained repeated injuries to the area. Histologically, the lesion was characterized by well-circumscribed lobules composed of small cellular aggregates, some in 'alveolar' distribution, and single, large, vacuolated (physalipherous) cells embedded within a hyalin and chondroid matrix divided by fibrous trabeculae. Immunohistochemically, the parachordoma stained positively for the S-100 protein, vimentin, and cytokeratin.

Original languageEnglish (US)
Pages (from-to)185-188
Number of pages4
JournalAmerican Journal of Dermatopathology
Volume16
Issue number2
DOIs
StatePublished - Jan 1 1994

Keywords

  • Chordoma
  • Parachordoma
  • Soft-tissue neoplasms

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

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