Panic Attacks and Phobias

Peter H. Keefe, W. Stewart Agras, Isaac Marks, Richard R. Neubig, Gregory Magarian, David A. Nardone, Douglas A. Hedlund, David V. Sheehan

Research output: Contribution to journalLetter

1 Citation (Scopus)

Abstract

To the Editor: Sheehan (July 15 issue1) cites double-blind, placebo-controlled studies as demonstrating the effectiveness of monoamine oxidase inhibitors and tricyclic antidepressants in treating spontaneous panic attacks.2 3 4 However, in all these studies, imipramine was given in a setting of in vivo exposure, supportive psychotherapy combined with instructions on exposure,2 , 3 or other, unspecified psychotherapy.4 In patients with agoraphobia who were treated by Zitrin et al.2 , 3 imipramine seemed to have an early effect on panic but was associated with a higher relapse rale than placebo at six months and one year (30 per cent for imipramine vs. 14 per cent.

Original languageEnglish (US)
Pages (from-to)341-343
Number of pages3
JournalNew England Journal of Medicine
Volume308
Issue number6
DOIs
StatePublished - Feb 10 1983
Externally publishedYes

Fingerprint

Phobic Disorders
Imipramine
Panic Disorder
Panic
Placebos
Agoraphobia
Monoamine Oxidase Inhibitors
Tricyclic Antidepressive Agents
Respiratory Sounds
Psychotherapy
Recurrence

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Keefe, P. H., Agras, W. S., Marks, I., Neubig, R. R., Magarian, G., Nardone, D. A., ... Sheehan, D. V. (1983). Panic Attacks and Phobias. New England Journal of Medicine, 308(6), 341-343. https://doi.org/10.1056/NEJM198302103080615

Panic Attacks and Phobias. / Keefe, Peter H.; Agras, W. Stewart; Marks, Isaac; Neubig, Richard R.; Magarian, Gregory; Nardone, David A.; Hedlund, Douglas A.; Sheehan, David V.

In: New England Journal of Medicine, Vol. 308, No. 6, 10.02.1983, p. 341-343.

Research output: Contribution to journalLetter

Keefe, PH, Agras, WS, Marks, I, Neubig, RR, Magarian, G, Nardone, DA, Hedlund, DA & Sheehan, DV 1983, 'Panic Attacks and Phobias', New England Journal of Medicine, vol. 308, no. 6, pp. 341-343. https://doi.org/10.1056/NEJM198302103080615
Keefe PH, Agras WS, Marks I, Neubig RR, Magarian G, Nardone DA et al. Panic Attacks and Phobias. New England Journal of Medicine. 1983 Feb 10;308(6):341-343. https://doi.org/10.1056/NEJM198302103080615
Keefe, Peter H. ; Agras, W. Stewart ; Marks, Isaac ; Neubig, Richard R. ; Magarian, Gregory ; Nardone, David A. ; Hedlund, Douglas A. ; Sheehan, David V. / Panic Attacks and Phobias. In: New England Journal of Medicine. 1983 ; Vol. 308, No. 6. pp. 341-343.
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