Pancreatitis caused by rheolytic thrombolysis: An unexpected complication

Jeffrey S. Danetz, Robert B. McLafferty, Juan Ayerdi, Lori A. Rolando, Zachary C. Schmittling, Don E. Ramsey, Kim J. Hodgson

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Two patients developed acute pancreatitis after mechanical thrombolysis with use of the AngioJet system. Patient 1 had undergone a remote complex revascularization of the lower extremities and presented with acute ischemia after thrombosis of his composite distal bypass. Patient 2 presented with superior vena cava (SVC) syndrome and had thrombosis of the SVC and innominate veins. Despite dissimilar presentations, both patients had renal insufficiency, were treated with mechanical and chemical thrombolysis, and had extensive thrombus burden. The pathophysiology of acute pancreatitis in this setting is believed to be secondary to massive hemolysis in the presence of chronic renal insufficiency. This phenomenon should be considered in patients whom develop abdominal pain after mechanical thrombolysis.

Original languageEnglish (US)
Pages (from-to)857-860
Number of pages4
JournalJournal of Vascular and Interventional Radiology
Issue number8
StatePublished - Aug 2004
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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