Oxygen reactions of the copper oxidases

James W. Whittaker

Research output: Contribution to journalArticle

15 Scopus citations

Abstract

The copper oxidases are a remarkable family of metalloenzymes that have evolved specialized mechanisms to accomplish the controlled reduction of dioxygen, delivering the equivalent of H2 from organic substrates to O2 to form hydrogen peroxide, a ubiquitous oxygen metabolite that is involved in a wide range of biological interactions. These enzymes display their virtuosity in dioxygen chemistry by harnessing the oxidizing power of that molecule not only during catalytic turnover, but also in transforming themselves in the biogenesis of their catalytic redox cofactor.

Original languageEnglish (US)
Pages (from-to)155-172
Number of pages18
JournalEssays in Biochemistry
Volume34
DOIs
StatePublished - Jan 1 1999

    Fingerprint

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

Cite this