Oxygen reactions of the copper oxidases

James Whittaker

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The copper oxidases are a remarkable family of metalloenzymes that have evolved specialized mechanisms to accomplish the controlled reduction of dioxygen, delivering the equivalent of H2 from organic substrates to O2 to form hydrogen peroxide, a ubiquitous oxygen metabolite that is involved in a wide range of biological interactions. These enzymes display their virtuosity in dioxygen chemistry by harnessing the oxidizing power of that molecule not only during catalytic turnover, but also in transforming themselves in the biogenesis of their catalytic redox cofactor.

Original languageEnglish (US)
Pages (from-to)155-172
Number of pages18
JournalEssays in Biochemistry
Volume34
StatePublished - 1999

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Oxygen
Metabolites
Hydrogen Peroxide
Oxidation-Reduction
Molecules
Substrates
Enzymes
copper oxidase

ASJC Scopus subject areas

  • Biochemistry

Cite this

Oxygen reactions of the copper oxidases. / Whittaker, James.

In: Essays in Biochemistry, Vol. 34, 1999, p. 155-172.

Research output: Contribution to journalArticle

Whittaker, J 1999, 'Oxygen reactions of the copper oxidases', Essays in Biochemistry, vol. 34, pp. 155-172.
Whittaker, James. / Oxygen reactions of the copper oxidases. In: Essays in Biochemistry. 1999 ; Vol. 34. pp. 155-172.
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