Overview: Membrane lipid peroxidation

Kathleen S. Montine, Joseph F. Quinn, Thomas J. Montine

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

Lipid peroxidation has been associated with many pathological conditions, especially age-related diseases. While this association is becoming tighter and the body of evidence strongly supporting a role for lipid peroxidation in the pathogenesis of atherosclerosis, cancer, and neurodegeneration, significant questions remain. What are the major sources of free radicals in each of these diseases? Answers to this question will have important therapeutic implications. What are the mechanisms by which lipid peroxidation contributes to the initiation or progression of disease? Answers to this question will deepen our understanding of the pathogenesis of age-related diseases.

Original languageEnglish (US)
Pages (from-to)11-26
Number of pages16
JournalAdvances in Cell Aging and Gerontology
Volume12
DOIs
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Aging
  • Geriatrics and Gerontology

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