Outside the p53 RING: Transcription Regulation by Chromatin-Bound MDM2

Abhinav K. Jain, Michelle C. Barton

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations

Abstract

Evidence mounts, via two studies published in Molecular Cell (Riscal et al., 2016; Wienken et al., 2016), that chromatin-bound MDM2 impacts pluripotency and metabolism to promote survival and proliferation of cancer cells, independently of p53 degradation. Evidence mounts, via two studies published in Molecular Cell (Riscal et al., 2016; Wienken et al., 2016), that chromatin-bound MDM2 impacts pluripotency and metabolism to promote survival and proliferation of cancer cells, independently of p53 degradation.

Original languageEnglish (US)
Pages (from-to)805-807
Number of pages3
JournalMolecular Cell
Volume62
Issue number6
DOIs
StatePublished - Jun 16 2016
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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