Out-of-hospital cardiac arrest with onset witnessed by emergency medical services: Implications for improvement in overall survival

Lauri Holmström, Kyndaron Reinier, Lorrel Toft, Henry Halperin, Angelo Salvucci, Jonathan Jui, Sumeet S. Chugh

Research output: Contribution to journalReview articlepeer-review

Abstract

Out-of-hospital cardiac arrest (OHCA) remains a major public health problem. Even in high-income countries, survival rates have plateaued in the range of ten percent, stimulating an ongoing interest in developing novel approaches to resuscitation. Emergency Medical Services (EMS)-witnessed OHCAs constitute a subgroup of overall OHCA that occur after the arrival of EMS, leading to rapid initiation of resuscitation and significantly improved survival. In this narrative review we summarize and interpret recent developments in knowledge of EMS-witnessed OHCA regarding prevalence, demographics, location, circumstances, survival outcomes and clinical profile. We examine the possibility of informing novel resuscitation approaches and enhancing mechanistic knowledge by studying EMS-witnessed OHCA, with the goal of improving overall survival from OHCA.

Original languageEnglish (US)
Pages (from-to)19-27
Number of pages9
JournalResuscitation
Volume175
DOIs
StatePublished - Jun 2022

Keywords

  • Cardiac arrest
  • Emergency medical services
  • Pulseless electrical activity
  • Sudden cardiac death
  • Survival
  • Ventricular fibrillation
  • Witnessed status

ASJC Scopus subject areas

  • Emergency Medicine
  • Emergency
  • Cardiology and Cardiovascular Medicine

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