This chapter reviews other parenteral anticoagulants–danaparoid which is a heparin like one and the direct thrombin inhibitors. Although heparin and its derivatives are the most commonly used parenteral anticoagulants, other agents are also used for this purpose. Since clinical trials showed most of these had no major advantages over heparin, use of most of these agents is restricted to patients with heparin induced thrombocytopenia. The exception is bivalirudin which is also used in patients with acute coronary syndromes undergoing interventions.
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