TY - JOUR
T1 - Osteosarcoma
T2 - Subtle, rare, and misleading plain film features
AU - Rosenberg, Z. S.
AU - Lev, S.
AU - Schmahmann, S.
AU - Steiner, G. C.
AU - Beltran, J.
AU - Present, D.
PY - 1995
Y1 - 1995
N2 - Osteosarcoma is a malignant, mesenchymal, osteoid, and bone-forming tumor [1-3]. In most cases, typical radiographic features clearly illustrate the aggressive bone-forming nature of the lesion. These features include long- bone metaphyseal location, mixed areas of lysis and sclerosis, cortical destruction, periosteal new bone, and soft-tissue mass. However, numerous factors contribute to misleading radiographic patterns of osteosarcoma. They include histologic low-grade, lytic, or minimally sclerotic lesions, early detection, confinement to the intramedullary canal, benign-appearing periosteal reaction, rare intraosseous locations (subchondral, diaphyseal, intracortical), and rare skeletal sites (e.g., soft tissues, skull, ribs, tarsal bones). Secondary osteosarcomas such as those arising from infarcts or fibrous dysplasia, may also produce a confusing radiologic picture. The purpose of this pictorial essay is to illustrate cases of osteosarcoma that proved to be difficult diagnostic dilemmas because of their subtle, rare, or misleading plain film features.
AB - Osteosarcoma is a malignant, mesenchymal, osteoid, and bone-forming tumor [1-3]. In most cases, typical radiographic features clearly illustrate the aggressive bone-forming nature of the lesion. These features include long- bone metaphyseal location, mixed areas of lysis and sclerosis, cortical destruction, periosteal new bone, and soft-tissue mass. However, numerous factors contribute to misleading radiographic patterns of osteosarcoma. They include histologic low-grade, lytic, or minimally sclerotic lesions, early detection, confinement to the intramedullary canal, benign-appearing periosteal reaction, rare intraosseous locations (subchondral, diaphyseal, intracortical), and rare skeletal sites (e.g., soft tissues, skull, ribs, tarsal bones). Secondary osteosarcomas such as those arising from infarcts or fibrous dysplasia, may also produce a confusing radiologic picture. The purpose of this pictorial essay is to illustrate cases of osteosarcoma that proved to be difficult diagnostic dilemmas because of their subtle, rare, or misleading plain film features.
UR - http://www.scopus.com/inward/record.url?scp=0028825350&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028825350&partnerID=8YFLogxK
U2 - 10.2214/ajr.165.5.7572505
DO - 10.2214/ajr.165.5.7572505
M3 - Article
C2 - 7572505
AN - SCOPUS:0028825350
SN - 0361-803X
VL - 165
SP - 1209
EP - 1214
JO - American Journal of Roentgenology
JF - American Journal of Roentgenology
IS - 5
ER -