Osteoma of long bone: an expanding spectrum of imaging findings

Barry Glenn Hansford, Peter Pytel, Drew D. Moore, Gregory Scott Stacy

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Osteoma of long bone is an extremely rare, benign bone-forming surface lesion with the largest published case series consisting of only 14 patients. The most important and often most difficult lesion to differentiate from osteoma of long bone radiographically is parosteal osteosarcoma, which is a rare, low-grade surface osteosarcoma with the potential for dedifferentiation. Reports of imaging studies of osteoma of long bone depict a well-defined ossified mass arising from the surface of the diaphysis or metadiaphysis of a long bone. A characteristic feature is the homogeneity of the mass, with uniform density near or equal to that of cortical bone from the base of the lesion to its periphery. The 45-year-old female in this case presented with left hip fullness and was subsequently found to have a proximal femoral osteoma, which was unique in that it contained large fatty marrow spaces that corresponded to bands of relatively low density on plain radiography and computed tomography, giving it a heterogeneous appearance atypical of osteoma of long bone. Furthermore, the osteoma reported here was associated with a small but separate nodular focus of ossification in the adjacent soft tissue. These findings led to a presumptive diagnosis of parosteal osteosarcoma with a local soft tissue metastasis or satellite nodule resulting in radical resection of the tumor. Definitive diagnosis of osteoma was made on histology of both the parent lesion and ossified nodule as no neoplastic spindle cell proliferation was present to establish a diagnosis of low-grade osteosarcoma. This represents, to the best of our knowledge, the first such presentation of osteoma of long bone.

Original languageEnglish (US)
Pages (from-to)755-761
Number of pages7
JournalSkeletal Radiology
Issue number5
StatePublished - Mar 18 2015
Externally publishedYes


  • Osteoma of long bone
  • Parosteal osteosarcoma
  • Surface lesion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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