Optimizing Hemodynamic Support in Septic Shock Using Central and Mixed Venous Oxygen Saturation

Supriya Maddirala, Akram Khan

Research output: Contribution to journalReview article

20 Scopus citations

Abstract

Global tissue hypoxia is one of the most important factors in the development of multisystem organ dysfunction. In hemodynamically unstable critically ill patients, central venous oxygen saturation (Scvo2) and mixed venous oxygen saturation (Svo2) monitoring has been shown to be a better indicator of global tissue hypoxia than vital signs and other clinical parameters alone. Svo2 is probably more representative of global tissue oxygenation, whereas Scvo2, is less invasive. Svo2 and Scvo2 monitoring can have diagnostic and therapeutic uses in understanding the efficacy of interventions in treating critically ill, hemodynamically unstable patients.

Original languageEnglish (US)
Pages (from-to)323-333
Number of pages11
JournalCritical Care Clinics
Volume26
Issue number2
DOIs
StatePublished - Apr 1 2010

Keywords

  • Central venous blood gas
  • Mixed venous blood gas
  • Sepsis
  • Septic shock

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

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