Optimization of the split-spectrum amplitudedecorrelation angiography algorithm on a spectral optical coherence tomography system

Simon S. Gao, Gangjun Liu, David Huang, Yali Jia

Research output: Contribution to journalArticle

79 Scopus citations

Abstract

The split-spectrum amplitude-decorrelation angiography algorithm was optimized on a spectral optical coherence tomography system using a flow phantom. The number of times the spectrum was split and the bandwidth of each split were adjusted to maximize the flow phantom decorrelation signal-to-noise ratio. The improvement in flow detection was then demonstrated with en face retinal angiograms. The optimized algorithm increased the detectable retinal microvascular flow and decreased the variability of the quantified vessel density in OCT retinal angiograms of healthy human subjects.

Original languageEnglish (US)
Pages (from-to)2305-2308
Number of pages4
JournalOptics Letters
Volume40
Issue number10
DOIs
StatePublished - 2015

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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