Optical manipulation of inorganic and organic objects in soft microfluidic devices

Cengiz S. Ozkan, Erhan Ata, Mihrimah Ozkan, Sadik C. Esener

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

We describe a technique for trapping and manipulation of inorganic and organic objects in microfluidic channels, based on photonic momentum transfer using an optical tweezers arrangement. Microfluidic devices have been fabricated by polydimethylsiloxane (PDMS) elastomer molding of patterns lithographically defined on a thick negative photoresist. Polystyrene microspheres dispersed in water were transferred into the fluidic channels using a syringe pump. Microspheres and live biological cells are trapped and redirected by optical manipulation within the fluidic channels. Optical trapping and patterning will have applications in creation of active cellular arrays for cell biology research, tissue engineering, cell sorting and drug discovery.

Original languageEnglish (US)
Pages (from-to)EE521-EE526
JournalMaterials Research Society Symposium - Proceedings
Volume657
StatePublished - Jan 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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