Optical manipulation of inorganic and organic objects in soft microfluidic devices

Cengiz S. Ozkan, Erhan Ata, Mihrimah Ozkan, Sadik Esener

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We describe a technique for trapping and manipulation of inorganic and organic objects in microfluidic channels, based on photonic momentum transfer using an optical tweezers arrangement. Microfluidic devices have been fabricated by polydimethylsiloxane (PDMS) elastomer molding of patterns lithographically defined on a thick negative photoresist. Polystyrene microspheres dispersed in water were transferred into the fluidic channels using a syringe pump. Microspheres and live biological cells are trapped and redirected by optical manipulation within the fluidic channels. Optical trapping and patterning will have applications in creation of active cellular arrays for cell biology research, tissue engineering, cell sorting and drug discovery.

Original languageEnglish (US)
JournalUnknown Journal
Volume657
StatePublished - 2001
Externally publishedYes

Fingerprint

Lab-On-A-Chip Devices
Optical Tweezers
Fluidics
Microspheres
Microfluidics
Cellular arrays
Cytology
Optics and Photonics
Elastomers
Optical tweezers
Syringes
Momentum transfer
Polystyrenes
Polydimethylsiloxane
Photoresists
Drug Discovery
Tissue Engineering
Sorting
Tissue engineering
Molding

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

Optical manipulation of inorganic and organic objects in soft microfluidic devices. / Ozkan, Cengiz S.; Ata, Erhan; Ozkan, Mihrimah; Esener, Sadik.

In: Unknown Journal, Vol. 657, 2001.

Research output: Contribution to journalArticle

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