Optical imaging of functional organization of V1 and V2 in marmoset visual cortex

Anna Roe, Kerstin Fritsches, John D. Pettigrew

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Using optical imaging of intrinsic cortical signals, we examined the functional organization of visual cortical areas V1 and V2 of the marmoset (Callithrix jacchus). Previous studies have reported that adult marmosets do not have ocular dominance columns (ODCs); however, recent studies have called this into question. Using optical imaging methods, we examined whether ODCs could be detected in adult marmosets. We found evidence for functional ODCs in some marmosets but not in others. The activation patterns, when present, were relatively weak and appeared as a mosaic of irregular bands or islands. Consistent with studies in other New World monkeys, these data suggest the presence of ODC variability within the marmoset population. Orientation maps in V1 revealed iso-orientation domains organized in semicontinuous bands oriented orthogonal to the V1/V2 border, a pattern unlike that in Macaque monkey. The presence of directional preference maps in V1 was also suggested. In V2, similar to V2 in Macaque monkeys, stripe-like regions of orientation selectivity overlay the pale cytochrome oxidase regions of V2; zones not selective for orientation overlay the cytochrome thin stripes. However, unlike Macaques, we did not observe clear evidence for orientation maps overlying thick cytochrome oxidase stripes. In sum, our data suggest that significant organizational differences exist between the organization of V1 and V2 in the marmoset and that of Old World primates. Implications for the establishment of functional ocular dominance columns, the coestablishment of multiple featural maps, and cortical magnification factors are discussed.

Original languageEnglish (US)
Pages (from-to)1213-1225
Number of pages13
JournalAnatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology
Volume287
Issue number2
DOIs
StatePublished - Dec 2005
Externally publishedYes

Fingerprint

Callithrix
Callitrichidae
Optical Imaging
Visual Cortex
ocular Dominance
image analysis
eyes
cytochrome
Macaca
cytochrome-c oxidase
Electron Transport Complex IV
monkeys
Haplorhini
imaging method
Cebidae
Callithrix jacchus
Platyrrhini
primate
cytochromes
Cytochromes

Keywords

  • Cortical magnification
  • New World primate
  • Ocular dominance columns
  • Orientation
  • V2 stripes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Anatomy

Cite this

Optical imaging of functional organization of V1 and V2 in marmoset visual cortex. / Roe, Anna; Fritsches, Kerstin; Pettigrew, John D.

In: Anatomical Record - Part A Discoveries in Molecular, Cellular, and Evolutionary Biology, Vol. 287, No. 2, 12.2005, p. 1213-1225.

Research output: Contribution to journalArticle

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