Optical coherence tomography (OCT) leading to more insight into cochlear mechanics

Egbert De Boer, Fangyi Chen, Dingjun Zha, Alfred Nuttall

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Optical Coherence Tomography (OCT) was used to measure vibrations of the basilar membrane (BM) and the Reticular Lamina (RL) in the cochlea of the Guinea pig, at frequencies up to 25...kHz. Because of the difficulty of the experiments the data have limited sets of parameters and are subject to high noise levels. In a viable Guinea-pig cochlea, the RL moves in the region of maximum response with a larger amplitude than the BM. We cannot rule out that some of that difference is due to a geometrical factor. We also found a consistent increase of this amplitude difference with frequency, which points to a low-pass filtering process. That process might be linked to the mass of the fluid contained in the Organ of Corti channel (OoC channel).

Original languageEnglish (US)
Title of host publicationMechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing
PublisherAmerican Institute of Physics Inc.
Volume1703
ISBN (Electronic)9780735413504
DOIs
StatePublished - Dec 31 2015
Event12th International Workshop on the Mechanics of Hearing: Protein to Perception - Cape Sounio, Greece
Duration: Jun 23 2014Jun 29 2014

Other

Other12th International Workshop on the Mechanics of Hearing: Protein to Perception
CountryGreece
CityCape Sounio
Period6/23/146/29/14

Fingerprint

guinea pigs
cochlea
tomography
membranes
organs
vibration
fluids

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

De Boer, E., Chen, F., Zha, D., & Nuttall, A. (2015). Optical coherence tomography (OCT) leading to more insight into cochlear mechanics. In Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing (Vol. 1703). [040004] American Institute of Physics Inc.. https://doi.org/10.1063/1.4939338

Optical coherence tomography (OCT) leading to more insight into cochlear mechanics. / De Boer, Egbert; Chen, Fangyi; Zha, Dingjun; Nuttall, Alfred.

Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. Vol. 1703 American Institute of Physics Inc., 2015. 040004.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

De Boer, E, Chen, F, Zha, D & Nuttall, A 2015, Optical coherence tomography (OCT) leading to more insight into cochlear mechanics. in Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. vol. 1703, 040004, American Institute of Physics Inc., 12th International Workshop on the Mechanics of Hearing: Protein to Perception, Cape Sounio, Greece, 6/23/14. https://doi.org/10.1063/1.4939338
De Boer E, Chen F, Zha D, Nuttall A. Optical coherence tomography (OCT) leading to more insight into cochlear mechanics. In Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. Vol. 1703. American Institute of Physics Inc. 2015. 040004 https://doi.org/10.1063/1.4939338
De Boer, Egbert ; Chen, Fangyi ; Zha, Dingjun ; Nuttall, Alfred. / Optical coherence tomography (OCT) leading to more insight into cochlear mechanics. Mechanics of Hearing: Protein to Perception - Proceedings of the 12th International Workshop on the Mechanics of Hearing. Vol. 1703 American Institute of Physics Inc., 2015.
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