Optical coherence tomography and ultrasound biomicroscopy imaging of opaque corneas

Shi You Zhou, Chun Xiao Wang, Xiao Yu Cai, David Huang, Yi Zhi Liu

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


PURPOSE:: The purpose was to determine the interchangeability of ultrasound biomicroscopy (UBM) and anterior segment optical coherence tomography (AS-OCT) for corneal opacity depth measurement. METHODS:: Twenty-six eyes of 26 consecutive patients with corneal opacities were examined by both AS-OCT and UBM. The corneal thickness and the corneal opacity depth were measured and compared. The interchangeability was determined by Bland-Altman plotting. RESULTS:: The difference in the full corneal thickness and in the corneal opacity depth between OCT and UBM was 5 ± 7 μm and-1 ± 8 μm, respectively. There were strong correlations and no significant differences between the paired parameters (all r > 0.99, P < 0.01). The limits of agreement were 5 ± 14 μm for the corneal thickness and-1 ± 14.8 μm for the corneal opacity depth. CONCLUSIONS:: AS-OCT and UBM may be used interchangeably for measuring both full corneal thickness and corneal opacity depth in patients with corneal opacity.

Original languageEnglish (US)
Pages (from-to)e25-e30
Issue number4
StatePublished - Apr 2013


  • anterior segment optical coherence tomography
  • cornea
  • corneal imaging
  • corneal opacity
  • ultrasound biomicroscopy

ASJC Scopus subject areas

  • Ophthalmology


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