Optical coherence tomographic angiography detects retinal vascular changes associated with pituitary adenoma

Ping Wei, Julie Falardeau, Aiyin Chen, Jie Wang, Liang Liu, Yali Jia, David Huang

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To report the distinct pattern of retinal perfusion loss captured on optical coherence tomographic angiography (OCTA) in a case of compressive optic neuropathy associated with pituitary adenoma. Observations: A 51-year-old male had bitemporal hemianopia caused by a pituitary adenoma that compressed the optic chiasm. OCTA scans in both eyes showed peripapillary nerve fiber layer plexus defects in the nasal hemispheres and papillomacular corridors. On macular scans, the ganglion cell layer plexus showed papillomacular defects. The perfusion defects corresponded with thinning on structural OCT measurement and loss of sensitivity on visual field tests. Conclusions and importance: Chiasm compression produces a characteristic pattern of perfusion loss that can be recognized OCTA. This knowledge may be useful in the diagnosis and classification of optic neuropathies.

Original languageEnglish (US)
Article number101711
JournalAmerican Journal of Ophthalmology Case Reports
Volume28
DOIs
StatePublished - Dec 2022

Keywords

  • Bitemporal hemianopia
  • OCT angiography
  • Pituitary adenoma

ASJC Scopus subject areas

  • Ophthalmology

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