Opioid analgesic misuse is associated with incomplete antiretroviral adherence in a cohort of HIV-infected indigent adults in San Francisco

Sara Jeevanjee, Joanne Penko, David Guzman, Christine Miaskowski, David Bangsberg, Margot B. Kushel

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

There is little or no data examining the association between either pain or the use or misuse of opioid analgesic with adherence to antiretroviral medications (ARVs) among HIV-infected adults. We interviewed a community-based cohort of HIV-infected indigent adults prescribed antiretroviral medications (ARVs) quarterly to examine the association between (1) pain, (2) receipt of opioid analgesics, and (3) opioid analgesic misuse with self-reported ARV adherence. Of 281 participants, most (82.5 %) reported severe or moderate pain, half (52.4 %) received a prescription for opioids, and one quarter (24.6 %) misused opioid analgesics. Most (71.9 %) reported >90 % ARV adherence. In a GEE model, neither pain (unadjusted OR 1.14, CI 0.90-1.45) nor prescription of opioid analgesics (unadjusted OR 1.11, CI 0.84-1.49) were significantly associated with ARV adherence. Misuse of opioid analgesics was associated with incomplete adherence (AOR 1.42, CI 1.09-1.86). Individuals who misuse opioid analgesics, like those who use illicit substances, may have difficulty adhering to medication regimens.

Original languageEnglish (US)
Pages (from-to)1352-1358
Number of pages7
JournalAIDS and Behavior
Volume18
Issue number7
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

San Francisco
Poverty
Opioid Analgesics
HIV
Pain
Prescriptions

Keywords

  • Analgesics
  • Antiretroviral therapy
  • Highly active
  • HIV infections
  • Medication adherence
  • Opioid
  • Opioid-related disorders
  • Pain

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

Opioid analgesic misuse is associated with incomplete antiretroviral adherence in a cohort of HIV-infected indigent adults in San Francisco. / Jeevanjee, Sara; Penko, Joanne; Guzman, David; Miaskowski, Christine; Bangsberg, David; Kushel, Margot B.

In: AIDS and Behavior, Vol. 18, No. 7, 2014, p. 1352-1358.

Research output: Contribution to journalArticle

Jeevanjee, Sara ; Penko, Joanne ; Guzman, David ; Miaskowski, Christine ; Bangsberg, David ; Kushel, Margot B. / Opioid analgesic misuse is associated with incomplete antiretroviral adherence in a cohort of HIV-infected indigent adults in San Francisco. In: AIDS and Behavior. 2014 ; Vol. 18, No. 7. pp. 1352-1358.
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