Opioid analgesic misuse is associated with incomplete antiretroviral adherence in a cohort of HIV-infected indigent adults in San Francisco

Sara Jeevanjee, Joanne Penko, David Guzman, Christine Miaskowski, David R. Bangsberg, Margot B. Kushel

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

There is little or no data examining the association between either pain or the use or misuse of opioid analgesic with adherence to antiretroviral medications (ARVs) among HIV-infected adults. We interviewed a community-based cohort of HIV-infected indigent adults prescribed antiretroviral medications (ARVs) quarterly to examine the association between (1) pain, (2) receipt of opioid analgesics, and (3) opioid analgesic misuse with self-reported ARV adherence. Of 281 participants, most (82.5 %) reported severe or moderate pain, half (52.4 %) received a prescription for opioids, and one quarter (24.6 %) misused opioid analgesics. Most (71.9 %) reported >90 % ARV adherence. In a GEE model, neither pain (unadjusted OR 1.14, CI 0.90-1.45) nor prescription of opioid analgesics (unadjusted OR 1.11, CI 0.84-1.49) were significantly associated with ARV adherence. Misuse of opioid analgesics was associated with incomplete adherence (AOR 1.42, CI 1.09-1.86). Individuals who misuse opioid analgesics, like those who use illicit substances, may have difficulty adhering to medication regimens.

Original languageEnglish (US)
Pages (from-to)1352-1358
Number of pages7
JournalAIDS and Behavior
Volume18
Issue number7
DOIs
StatePublished - Jul 2014

Keywords

  • Analgesics
  • Antiretroviral therapy
  • HIV infections
  • Highly active
  • Medication adherence
  • Opioid
  • Opioid-related disorders
  • Pain

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Opioid analgesic misuse is associated with incomplete antiretroviral adherence in a cohort of HIV-infected indigent adults in San Francisco'. Together they form a unique fingerprint.

  • Cite this