'Omic approaches to preventing or managing metastatic breast cancer

Obi L. Griffith, Joe W. Gray

Research output: Contribution to journalReview article

14 Scopus citations

Abstract

Early detection of metastasis-prone breast cancers and characterization of residual metastatic cancers are important in efforts to improve management of breast cancer. Applications of genome-scale molecular analysis technologies are making these complementary approaches possible by revealing molecular features uniquely associated with metastatic disease. Assays that reveal these molecular features will facilitate development of anatomic, histological and blood-based strategies that may enable detection prior to metastatic spread. Knowledge of these features also will guide development of therapeutic strategies that can be applied when metastatic disease burden is low, thereby increasing the probability of a curative response.

Original languageEnglish (US)
Article number230
JournalBreast Cancer Research
Volume13
Issue number6
DOIs
StatePublished - Dec 8 2011

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ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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