Omega-3 fatty acids: Cardiovascular benefits, sources and sustainability

John H. Lee, James H. O'Keefe, Carl J. Lavie, William Harris

Research output: Contribution to journalArticle

125 Citations (Scopus)

Abstract

The evidence for the cardioprotective nature of omega-3 fatty acids is abundant, and currently available data indicate that patients with known coronary heart disease should consume at least 1 g daily of long-chain omega-3 fatty acids from either oily fish or fish-oil supplements, and that individuals without disease should consume at least 250-500 mg daily. However, this area of research poses two questions. Firstly, which is the best source of omega-3 fatty acids-fish or fish-oil supplements? Secondly, are recommendations for omega-3 supplementation warranted in view of the rapid depletion of world fish stocks? The argument that eating fish is better than taking fish-oil supplements stems from the fact that several important nutrients, such as vitamin D, selenium, and antioxidants, are missing from the supplements. However, three major prevention trials have clearly indicated that omega-3 fatty acid capsules confer cardiovascular benefits and, therefore, that both are cardioprotective. Sustainable sources of omega-3 fatty acids will need to be identified if long-term cardiovascular risk reduction is to be achieved at the population level.

Original languageEnglish (US)
Pages (from-to)753-758
Number of pages6
JournalNature Reviews Cardiology
Volume6
Issue number12
DOIs
StatePublished - Dec 1 2009
Externally publishedYes

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Omega-3 Fatty Acids
Fish Oils
Fishes
Risk Reduction Behavior
Selenium
Vitamin D
Capsules
Coronary Disease
Eating
Antioxidants
Food
Research
Population

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Medicine(all)

Cite this

Omega-3 fatty acids : Cardiovascular benefits, sources and sustainability. / Lee, John H.; O'Keefe, James H.; Lavie, Carl J.; Harris, William.

In: Nature Reviews Cardiology, Vol. 6, No. 12, 01.12.2009, p. 753-758.

Research output: Contribution to journalArticle

Lee, John H. ; O'Keefe, James H. ; Lavie, Carl J. ; Harris, William. / Omega-3 fatty acids : Cardiovascular benefits, sources and sustainability. In: Nature Reviews Cardiology. 2009 ; Vol. 6, No. 12. pp. 753-758.
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